Evidence map›Paper›PMID 34525896›Full record

ArticleCurrent medical research and opinion2021

In-hospital mortality, length of stay and hospital costs for hospitalized breast cancer patients with comorbid heart failure in the USA.

Chanhyun Park, Sun-Kyeong Park, Jenica N Upshaw, Mara A Schonberg

Open access · greenAbstract read
In one paragraph

Article in Current medical research and opinion, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Chanhyun ParkHealth Outcomes Division, College of Pharmacy, The University of Texas at Austin, Austin, TX, USA.ORCID 0000-0002-1081-0950
Sun-Kyeong ParkSchool of Pharmacy, The Catholic University of Korea, Bucheon, South Korea.
Jenica N UpshawDivision of Cardiology, Tufts Medical Center, Boston, MA, USA.
Mara A SchonbergDivision of General Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Beth Israel Deaconess Medical Center · USThe Catholic University of Korea Bucheon St. Mary's Hospital · KRThe University of Texas at Austin · USTufts Medical Center · US

Funding

Research and mentoring program in shared decision making in the care of older adultsK24AG071906 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI SCHONBERG, MARA A · 2021 to 2025
$946k
Prevention of Anthracycline Chemotherapy CardiotoxicityK08HL146959 · NHLBI · TUFTS MEDICAL CENTER · PI UPSHAW, JENICA · 2020 to 2024
$885k
NHLBI NIH HHS K08 HL146959NIA NIH HHS K24 AG071906
6 · The paper itself

Abstract

objectivesBreast cancer and heart failure (HF) are frequently interconnected due to shared risk factors and the cardiotoxicity of breast cancer treatment. However, the association between HF and hospital outcomes among breast cancer patients has not been studied. This study examined the association between HF and hospital outcomes among hospitalized patients with breast cancer.

methodsThis cross-sectional study using the 2015-2018 Healthcare Cost and Utilization Project-National Inpatient Sample data included hospitalized women who were aged 18 years or older and had a primary diagnosis code for breast cancer. Logistic regression, negative binomial regression, and generalized linear models with log-link and gamma distribution were used to assess the associations of HF with in-hospital mortality, length of stay (LOS) and hospital costs.

resultsAmong 17,335 hospitalized patients with breast cancer, 4.2% (

conclusionHF has a substantial negative impact on health outcomes among hospitalized breast cancer patients. Breast cancer and HF are often considered separate medical conditions, but promoting effective management of comorbid HF in breast cancer patients may help to improve hospital outcomes in this population.

Indexed as

Breast NeoplasmsHeart FailureCross-Sectional StudiesFemaleHospital CostsHospitalizationHospital MortalityHospitalsHumansLength of StayUnited StatesBreast cancerheart failurehospital costsin-hospital mortalitylength of stay

Identifiers

PMID34525896
PMCPMC9627537
OpenAlexW3199660983

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.