ReviewProgress in neurobiology2021
Imaging faster neural dynamics with fast fMRI: A need for updated models of the hemodynamic response.
Review in Progress in neurobiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 1 of them a synthesis that pooled it.
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Who cites it
68 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Simultaneous mesoscopic imaging of neural activity and hemodynamics reveals anesthetic modulation of neurovascular responses.Photoacoustics · 2026Article
- Simultaneous single-cell calcium imaging of neuronal population activity and brain-wide BOLD fMRI.Nature methods · 2026Article
- Revisiting the auditory hemodynamic response function in the era of fast fMRI.bioRxiv : the preprint server for biology · 2026Article
- Large gains in SNR through the application of Shinnar-Le Roux RF pulse design to short-TR spin-echo fMRI acquisitions at 7 T.Magnetic resonance imaging · 2026Article
- Effect of ketamine intervention on hemodynamic responses in patients with treatment-resistant depression.Scientific reports · 2026Article
- Somatosensory Evoked BOLD-Signals With Ultra-High Temporal Resolution.Human brain mapping · 2026Article
- Inferring neural sources from electroencephalography: foundations and frontiers.Journal of neural engineering · 2026Review
- Divergence unveils further distinct phenotypic traits of human brain connectomics fingerprint.iScience · 2026Article
- Biophysical simulations of fMRI responses using realistic microvascular models: Insights into distinct hemodynamics in humans and mice.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- Reconstructing brain causal dynamics for subject and task fingerprints using fMRI time-series data.Health information science and systems · 2025Article
- Functional MRI signals as fast as 1Hz are coupled to brain states and predict spontaneous neural activity.bioRxiv : the preprint server for biology · 2025Article
- Evaluating BOLD functional MRI biophysical simulation approaches: impact of vascular geometry, magnetic field calculations, and water diffusion models.bioRxiv : the preprint server for biology · 2025Article
- Brainwide hemodynamics predict EEG neural rhythms across sleep and wakefulness in humans.PLoS computational biology · 2025Article
- Towards whole brain mapping of the hemodynamic response function.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2025Article
- Visual stimulus-evoked blood velocity responses in individual human posterior cerebral arteries measured with dynamic phase-contrast functional MR angiography.bioRxiv : the preprint server for biology · 2025Article
- What are we missing? What are we assuming? The need to foster feature discovery tools to improve statistical models.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Brainwide hemodynamics predict EEG neural rhythms across sleep and wakefulness in humans.bioRxiv : the preprint server for biology · 2025Article
- An fNIRS dataset for Multimodal Speech Comprehension in Normal Hearing Individuals and Cochlear Implant Users.Scientific data · 2025Article
- Neural signatures of emotional intent and inference align during social consensus.Nature communications · 2025Article
8 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors.
Funding
Abstract
Fast fMRI enables the detection of neural dynamics over timescales of hundreds of milliseconds, suggesting it may provide a new avenue for studying subsecond neural processes in the human brain. The magnitudes of these fast fMRI dynamics are far greater than predicted by canonical models of the hemodynamic response. Several studies have established nonlinear properties of the hemodynamic response that have significant implications for fast fMRI. We first review nonlinear properties of the hemodynamic response function that may underlie fast fMRI signals. We then illustrate the breakdown of canonical hemodynamic response models in the context of fast neural dynamics. We will then argue that the canonical hemodynamic response function is not likely to reflect the BOLD response to neuronal activity driven by sparse or naturalistic stimuli or perhaps to spontaneous neuronal fluctuations in the resting state. These properties suggest that fast fMRI is capable of tracking surprisingly fast neuronal dynamics, and we discuss the neuroscientific questions that could be addressed using this approach.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.