Evidence map›Paper›PMID 34525244›Full record

ArticleDigestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society2022

Long-term outcomes of standardized colonic stenting using WallFlex as a bridge to surgery: Multicenter prospective cohort study.

Toshio Kuwai, Yuzuru Tamaru, Ryusaku Kusunoki, Shuntaro Yoshida, Takeaki Matsuzawa, Hiroyuki Isayama, Iruru Maetani, Mamoru Shimada, Tomonori Yamada, Shuji Saito and 5 more

Abstract readMulticenter Study
In one paragraph

Article in Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Usefulness of an ultrathin endoscope for guidewire insertion during stent-in-stent placement.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2023
    Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Challenges in colonic stenting: Giving up is not an option.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2022
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Toshio KuwaiDepartment of Gastroenterology, National Hospital Organization Kure Medical Center and Chugoku Cancer Center, Hiroshima, Japan.ORCID https://orcid.org/0000-0001-9956-1358
Yuzuru TamaruDepartment of Gastroenterology, National Hospital Organization Kure Medical Center and Chugoku Cancer Center, Hiroshima, Japan.
Ryusaku KusunokiDepartment of Gastroenterology, National Hospital Organization Kure Medical Center and Chugoku Cancer Center, Hiroshima, Japan.
Shuntaro YoshidaDepartment of Endoscopy and Endoscopic Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0002-9437-9132
Takeaki MatsuzawaDepartment of Surgery, Imusumiyoshi General Hospital, Saitama, Japan.
Hiroyuki IsayamaDepartment of Gastroenterology, Graduate School of Medicine, Juntendo University, Tokyo, Japan.
Iruru MaetaniDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0002-9072-3805
Mamoru ShimadaDepartment of Surgery, Toyonaka Keijinkai Hospital, Osaka, Japan.
Tomonori YamadaDepartment of Gastroenterology, Japanese Red Cross Nagoya Daini Hospital, Aichi, Japan.
Shuji SaitoDivision of Surgery, Gastrointestinal Center, Yokohama Shin-Midori General Hospital, Kanagawa, Japan.
Masafumi TomitaDepartment of Surgery, Kobe Tokushukai Hospital, Hyogo, Japan.
Koichi KoizumiDepartment of Gastroenterology, Tokyo Metropolitan Cancer and Infectious Disease Center, Komagome Hospital, Tokyo, Japan.
Toshiyasu ShiratoriDepartment of Gastroenterology, Kameda Medical Center, Chiba, Japan.
Toshiyuki EnomotoDepartment of Surgery, Toho University Ohashi Medical Center, Tokyo, Japan.
Yoshihisa SaidaDepartment of Surgery, Toho University Ohashi Medical Center, Tokyo, Japan.

Funding

Japanese Gastroenterological Endoscopy SocietyThe Japan Colonic Stent Safe Procedure Research Group
6 · The paper itself

Abstract

objectivesThe oncological outcomes, especially high recurrence rate, of bridge-to-surgery (BTS) self-expandable metallic stent (SEMS) placement remain concerning, emphasizing the necessity of standardized SEMS placement. However, its impact on long-term BTS outcomes is unknown. We investigated the long-term outcomes of BTS colonic stenting using standardized SEMS placement.

methodsThis prospective, multicenter cohort study conducted at 46 hospitals in Japan (March 2012 to October 2013) included consecutive patients with stage II and III obstructive colorectal cancer managed with BTS SEMS placement. The SEMS placement technique was standardized by information dissemination among the participating hospitals. The primary outcome was overall survival (OS) after SEMS placement, and the secondary outcomes were relapse-free survival (RFS), recurrence, and short-term outcomes of SEMS placement and surgery.

resultsThe 1-, 3-, and 5-year OS rates were 94.1%, 77.4%, and 67.4% (Kaplan-Meier), respectively, with high technical success (99.0%, 206/208) and low perforation (1.9%, 4/208) rates. The 1-, 3-, and 5-year RFS rates were 81.6%, 65.6%, and 57.9% (Kaplan-Meier), respectively, and the overall recurrence rate was 31.0% (62/200). The RFS rate was significantly poorer in patients with perforation (n = 4) than in those without perforation (n = 196) (log-rank P = 0.017); moreover, perforation was identified as an independent factor affecting RFS (hazard ratio 3.31; 95% confidence interval 1.03-10.71, multivariate Cox regression).

conclusionThis large, prospective, multicenter study revealed satisfactory long-term outcomes of BTS colonic stenting using a standardized SEMS insertion method, which might be specifically due to the reduced perforation rate. (UMIN000007953).

Indexed as

Colonic NeoplasmsColorectal NeoplasmsIntestinal ObstructionSelf Expandable Metallic StentsCohort StudiesHumansNeoplasm Recurrence, LocalProspective StudiesRetrospective StudiesStentsTreatment Outcomebridge to surgerycolorectal cancerperforationself-expandable metallic stentstenting

Identifiers

PMID34525244
PMCPMC9293325

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.