ArticlePloS one2021
Update: Gender differences in CABG outcomes-Have we bridged the gap?
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review and meta-analysis of differences between men and women in short-term outcomes following coronary artery bypass graft surgery.Scientific reports · 2024Pooled it
- Sex Differences in Long-term Outcomes Following Coronary Artery Bypass Grafting: A Nationwide Population-Based Propensity Score-Matched Cohort Study.Journal of Korean medical science · 2026Article
- Investigating clinical practice variations in coronary artery disease treatment using reinforcement and transfer learning.NPJ cardiovascular health · 2026Article
- Targeting the CD39/CD73 pathway: New insights into cardiac fibrosis and inflammation in female cardiac surgery patients.Journal of molecular and cellular cardiology plus · 2025Article
- Unfavorable impact of female gender on outcomes following aortic valve replacement combined with coronary artery bypass grafting.Scientific reports · 2025Article
- Long-term mortality after coronary surgery in women patients depend on diabetes and age.Interdisciplinary cardiovascular and thoracic surgery · 2025Article
- Long-term outcomes of women compared to men after off-pump coronary artery bypass grafting-a propensity-matched analysis.Indian journal of thoracic and cardiovascular surgery · 2025Article
- Assessing hemodynamic changes before and after pump in CABG surgery and its factors.ARYA atherosclerosis · 2025Article
- Sex Disparities in In-Hospital Outcomes After Percutaneous Coronary Intervention (PCI) in Patients With Acute Myocardial Infarction and a History of Coronary Artery Bypass Grafting (CABG): A Cross-Sectional Study.Health science reports · 2024Article
- Cellular Characteristics and Protein Signatures of Human Adipose Tissues from Donors With or Without Advanced Coronary Artery Disease.Biomedicines · 2024Article
- Sex-based association between high-density lipoprotein cholesterol and adverse outcomes after coronary artery bypass grafting.BMC cardiovascular disorders · 2024Article
- Sex differences in outcomes of patients undergoing on-pump coronary artery bypass grafting surgery.PloS one · 2024Observational
- Predictors of Premature Mortality Following Coronary Artery Bypass Grafting: An Iranian Single-Centre Study.Healthcare (Basel, Switzerland) · 2023Article
- Article
- Minimally invasive surgical coronary artery bypass in women.Annals of cardiothoracic surgery · 2023Article
- Predictors of Nocturnal Hypoxemic Burden in Patients Undergoing Elective Coronary Artery Bypass Grafting Surgery.Biomedicines · 2023Article
- Female gender does not have any significant impact on the early postoperative outcomes after coronary artery bypass grafting: a propensity-matched analysis.Indian journal of thoracic and cardiovascular surgery · 2023Article
- Effect of Gender on Postoperative Outcome and Duration of Ventilation After Coronary Artery Bypass Grafting (CABG).Cureus · 2023Article
- Presentation and Outcomes of Patients With Preoperative Critical Illness Undergoing Cardiac Surgery.JACC. Advances · 2023Article
- Effects of blood transfusion, cardiopulmonary bypass time, and bypassed vessels on mortality following isolated and combined coronary artery bypass grafting.American journal of cardiovascular disease · 2023Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAppreciation of unique presentation, patterns and underlying pathophysiology of coronary artery disease in women has driven gender based risk stratification and risk reduction efforts over the last decade. Data regarding whether these advances have resulted in unequivocal improvements in outcomes of CABG in women is conflicting. The objective of our study was to assess gender differences in post-operative outcomes following CABG.
methodsRetrospective analyses of institutional data housed in the Society of Thoracic Surgeons (STS) database for patients undergoing CABG between 2002 and 2020 were conducted. Multivariable regression analysis was conducted to investigate gender differences in post-operative outcomes. P-values were adjusted using Bonferroni correction to reduce type-I errors.
resultsOur final cohort of 6,250 patients had fewer women than men (1,339 vs. 4,911). more women were diabetic (52.0% vs. 41.2%, p<0.001) and hypertensive (89.1% vs. 84.0%, p<0.001). Women had higher adjusted odds of developing ventilator dependence >48 hours (OR: 1.65 [1.21, 2.45], p = 0.002) and cardiac readmissions (OR: 1.56 [1.27, 2.30], p = 0.003). After adjustment for comorbidity burden, mortality rates in women were comparable to those of age-matched men.
conclusionThe findings of our study indicate that despite apparent reduction of differences in mortality, the burden of postoperative morbidity is still high among women.
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