Evidence map›Paper›PMID 34525102›Full record

ArticlePloS one2021

Refractive changes of a new asymmetric intracorneal ring segment with variable thickness and base width: A 2D finite-element model.

Gonzalo García de Oteyza, Juan Álvarez de Toledo, Rafael I Barraquer, Sabine Kling

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Gonzalo García de OteyzaClínica Oftalmológica García de Oteyza, Barcelona, Spain.ORCID 0000-0002-8169-8791
Juan Álvarez de ToledoCentro de Oftalmología Barraquer, Barcelona, Spain.
Rafael I BarraquerCentro de Oftalmología Barraquer, Barcelona, Spain.
Sabine KlingDepartment of Information Technology and Electrical Engineering, OPTIC Team, Computer-assisted Applications in Medicine Group, ETH Zurich, Zurich, Switzerland.ORCID 0000-0001-7202-7200
Barraquer Opthalmology Center · ESETH Zurich · CHUniversitat Autònoma de Barcelona · ESUniversitat Internacional de Catalunya · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the local geometric effects of a unilateral intrastromal ring segment with a combined variation of ring thickness and base width in a finite element simulation, and to compare it against the isolated effect of thickness or base width variation alone.

methodsA two-dimensional finite-element model of a transversely isotropic cornea was created assuming either axisymmetric stress or plane strain condition. The model geometry was composed of a three-layered corneal tissue (epithelium, anterior and posterior stroma) fixed at the limbus. The implantation of a triangular-shape asymmetric ring segment with varying ring thickness (150 to 300 μm) and base width (600 to 800 μm) was simulated. Also, changes induced by thickness or base width alone were studied and compared their combined effect in the asymmetric ring segment. Geometrical deformation of the simulated cornea and sagittal curvature were the main parameters of study.

resultsIncreasing ring thickness and base width along the arc of the asymmetric ring segment produced a more pronounced flattening in this part of the ring. The asymmetric design did find a good balance between maximizing corneal flattening at one end and minimizing it at the other end, compared to the isolated effect of ring thickness and width. Ring thickness was the most robust parameter in flattening both, the central and peripheral cornea.

conclusionThe finite-element model permitted a theoretical study of corneal deformation undergoing implantation of realistic and hypothetical ring geometries. Intracorneal asymmetric ring segments with varying thickness and base width can be a good alternative in corneas with asymmetric keratoconus phenotypes.

Indexed as

Corneal TopographyOphthalmologic Surgical ProceduresRefraction, OcularComputer SimulationCorneaCorneal StromaEye, ArtificialFinite Element AnalysisHumansKeratoconusProsthesis ImplantationSoftwareVision Tests

Identifiers

PMID34525102
PMCPMC8443075
OpenAlexW3199391753

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.