Evidence map›Paper›PMID 34524978›Full record

ArticleEndocrine connections2021

Assessment of different markers of ovarian reserve in women with papillary thyroid cancer treated with radioactive iodine.

Agnieszka Adamska, Paulina Tomczuk-Bobik, Anna Beata Popławska-Kita, Katarzyna Siewko, Angelika Buczyńska, Piotr Szumowski, Łukasz Żukowski, Janusz Myśliwiec, Monika Zbucka-Krętowska, Marcin Adamski and 1 more

Open access · goldAbstract read
In one paragraph

Article in Endocrine connections, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Agnieszka AdamskaDepartment of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Białystok, Poland.
Paulina Tomczuk-BobikDepartment of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Białystok, Poland.
Anna Beata Popławska-KitaDepartment of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Białystok, Poland.
Katarzyna SiewkoDepartment of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Białystok, Poland.
Angelika BuczyńskaClinical Research Centre, Medical University of Bialystok, Białystok, Poland.
Piotr SzumowskiDepartment of Nuclear Medicine, Medical University of Białystok, Białystok, Poland.
Łukasz ŻukowskiDepartment of Nuclear Medicine, Medical University of Białystok, Białystok, Poland.
Janusz MyśliwiecDepartment of Nuclear Medicine, Medical University of Białystok, Białystok, Poland.
Monika Zbucka-KrętowskaDepartment of Gynecological Endocrinology and Adolescent Gynecology, Medical University of Bialystok, Białystok, Poland.
Marcin AdamskiFaculty of Computer Science, Bialystok University of Technology, Białystok, Poland.
Adam Jacek KrętowskiDepartment of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Białystok, Poland.
Medical University of Białystok · PLBialystok University of Technology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment with radioactive iodine (RAI) in women with differentiated thyroid cancer is associated with decreased serum concentrations of anti-Müllerian hormone (AMH); however, other markers have not been investigated. Therefore, this study aimed to evaluate the effect of RAI treatment on antral follicle count (AFC) and the serum concentration of inhibin B, follicle-stimulating hormone (FSH), and AMH in women with papillary thyroid cancer (PTC) treated with RAI. We examined 25 women at a median age of 33 years treated with a single dose of RAI. We divided the participants into women over (n = 11) and under 35 years of age (n = 14). Serum concentrations of inhibin B, FSH, AMH, and AFC were assessed at baseline and 1 year after RAI treatment. We found decreased AFC (P = 0.03), serum levels of AMH (P < 0.01), inhibin B (P = 0.03), but not FSH (P = 0.23), 1 year after RAI treatment in comparison to baseline in the whole group. When we compared serum levels of AMH in younger vs older women separately, we observed a significant reduction of this hormone's serum level after RAI treatment in both groups (P < 0.01; P = 0.04, respectively). We concluded that RAI treatment significantly impacts the functional ovarian reserve in premenopausal women with PTC.

Indexed as

AMHovarian reservePTCRAI

Identifiers

PMID34524978
PMCPMC8558897
OpenAlexW3200683475

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.