Evidence map›Paper›PMID 34524872›Full record

ArticleMolecular biology of the cell2021

Ensconsin-dependent changes in microtubule organization and LINC complex-dependent changes in nucleus-nucleus interactions result in quantitatively distinct myonuclear positioning defects.

Mary Ann Collins, L Alexis Coon, Riya Thomas, Torrey R Mandigo, Elizabeth Wynn, Eric S Folker

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Cells · 2025
    Review
  2. Article
  3. Review
  4. Nuclear movement in multinucleated cells.Development (Cambridge, England) · 2022
    Review
  5. Mechanics and functional consequences of nuclear deformations.Nature reviews. Molecular cell biology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mary Ann CollinsDepartment of Biology, Boston College, Chestnut Hill, MA 02467.
L Alexis CoonDepartment of Biology, Boston College, Chestnut Hill, MA 02467.
Riya ThomasDepartment of Biology, Boston College, Chestnut Hill, MA 02467.
Torrey R MandigoDepartment of Biology, Boston College, Chestnut Hill, MA 02467.
Elizabeth WynnDepartment of Biology, Boston College, Chestnut Hill, MA 02467.
Eric S FolkerDepartment of Biology, Boston College, Chestnut Hill, MA 02467.
Boston College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nuclear movement is a fundamental process of eukaryotic cell biology. Skeletal muscle presents an intriguing model to study nuclear movement because its development requires the precise positioning of multiple nuclei within a single cytoplasm. Furthermore, there is a high correlation between aberrant nuclear positioning and poor muscle function. Although many genes that regulate nuclear movement have been identified, the mechanisms by which these genes act are not known. Using

Indexed as

AnimalsBiological TransportCell NucleusDrosophila melanogasterDrosophila ProteinsKinesinsMicrotubule-Associated ProteinsMicrotubule-Organizing CenterMicrotubule ProteinsMicrotubulesMuscle, SkeletalNuclear EnvelopeDrosophila ProteinsKinesinsMicrotubule-Associated ProteinsMicrotubule Proteins

Identifiers

PMID34524872
PMCPMC8693964
OpenAlexW3199251687

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.