ArticleOrganic letters2021
Regioselective Monoborylation of Spirocyclobutenes.
Article in Organic letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Synthesis and Ring Expansion of Triflylated Cyclobutenyl MIDA Boronates.Organic letters · 2026Article
- Enantioselective photocatalytic synthesis of bicyclo[2.1.1]hexanes as ortho-disubstituted benzene bioisosteres with improved biological activity.Nature chemistry · 2025Article
- Photoredox cobalt-catalyzed asymmetric desymmetric reductive coupling of cyclobutenes with alkynes.Nature communications · 2025Article
- Borylated cyclobutanesChemical science · 2024Article
- Rhodium-Catalyzed Asymmetric Arylation of Cyclobutenone Ketals.Angewandte Chemie (International ed. in English) · 2023Article
- Updated Progress of the Copper-Catalyzed Borylative Functionalization of Unsaturated Molecules.Molecules (Basel, Switzerland) · 2023Review
- Enantioselective Suzuki cross-coupling of 1,2-diboryl cyclopropanes.Chemical science · 2023Article
- Synthesis of 3-borylated cyclobutanols from epihalohydrins or epoxy alcohol derivatives.Chemical science · 2023Article
- Arylboration of Enecarbamates for the Synthesis of Borylated Saturated N-Heterocycles.Angewandte Chemie (International ed. in English) · 2022Article
- Boosting the Enantioselectivity of Conjugate Borylation of α,β-Disubstituted Cyclobutenones with Monooxides of Chiral CChemistry (Weinheim an der Bergstrasse, Germany) · 2022Article
- Photosensitized [2+2]-Cycloadditions of Alkenylboronates and Alkenes.Angewandte Chemie (International ed. in English) · 2022Article
- Catalytic asymmetric hydrometallation of cyclobutenes with salicylaldehydes.Chemical science · 2021Article
- Catalytic Arylboration of Spirocyclic Cyclobutenes: Rapid Access to Highly Substituted Spiro[3.n]alkanes.ACS catalysis · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We present a strategy for the synthesis of spirocyclic cyclobutanes with modulable exit vectors based on the regioselective monoborylation of spirocyclobutenes. Using an inexpensive copper salt and a commercially available bidentate phosphine, a broad variety of borylated spirocycles have been prepared with complete regiocontrol. The boryl moiety provides a synthetic handled for further functionalization, allowing access to a wide array of spirocyclic building blocks from a common intermediate.
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