Evidence map›Paper›PMID 34524697›Full record

ReviewJournal of medical virology2022

Genetic drift in the genome of SARS COV-2 and its global health concern.

Iqra Bano, Mehmoona Sharif, Sadia Alam

Open access · greenAbstract readReview
In one paragraph

Review in Journal of medical virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

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  14. Life barcoded by DNA barcodes.Conservation genetics resources · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Iqra BanoDepartment of Microbiology, The University of Haripur, Haripur, Pakistan.
Mehmoona SharifDepartment of Microbiology, Quaid I Azam University, Islamabad, Pakistan.
Sadia AlamDepartment of Microbiology, The University of Haripur, Haripur, Pakistan.ORCID 0000-0003-3102-8252
University of Haripur · PKQuaid-i-Azam University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The outbreak of the current coronavirus disease (COVID-19) occurred in late 2019 and quickly spread all over the world. The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) belongs to a genetically diverse group that mutates continuously leading to the emergence of multiple variants. Although a few antiviral agents and anti-inflammatory medicines are available, thousands of individuals have passed away due to emergence of new viral variants. Thus, proper surveillance of the SARS-CoV-2 genome is needed for the rapid identification of developing mutations over time, which are of the major concern if they occur specifically in the surface spike proteins of the virus (neutralizing analyte). This article reviews the potential mutations acquired by the SARS-CoV2 since the pandemic began and their significant impact on the neutralizing efficiency of vaccines and validity of the diagnostic assays.

Indexed as

Genetic DriftAntibodies, NeutralizingCOVID-19Gene FrequencyGenetic VariationGenome, ViralHumansImmunogenicity, VaccineRNA, ViralSARS-CoV-2Spike Glycoprotein, CoronavirusAntibodies, NeutralizingRNA, ViralSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2COVID-19geneticsmutationSARS-CoV-2serodiagnosisvaccinationvariants

Identifiers

PMID34524697
PMCPMC8661852
OpenAlexW3199661569

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.