Evidence map›Paper›PMID 34524590›Full record

ReviewWiener medizinische Wochenschrift (1946)2023

Hashimoto's thyroiditis and coexisting disorders in correlation with HLA status-an overview.

Peter Mikosch, Adrian Aistleitner, Markus Oehrlein, Eva Trifina-Mikosch

Open access · hybridAbstract readReview
In one paragraph

Review in Wiener medizinische Wochenschrift (1946), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Autoimmune Hepatitis Associated with Other Autoimmune Diseases: A Critical Review.Journal of clinical and translational hepatology · 2025
    Review
  7. Study of theDiagnostics (Basel, Switzerland) · 2025
    Article
  8. ExploringReports of biochemistry & molecular biology · 2025
    Article
  9. Alcohol Consumption and Autoimmune Diseases.International journal of molecular sciences · 2025
    Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Peter MikoschTeaching Unit, Medizinische Universität Wien/Medical University Vienna, Vienna, Austria. peter.mikosch@meduniwien.ac.at.ORCID http://orcid.org/0000-0001-7181-9062
Adrian AistleitnerTeaching Unit, Medizinische Universität Wien/Medical University Vienna, Vienna, Austria.
Markus OehrleinTeaching Unit, Medizinische Universität Wien/Medical University Vienna, Vienna, Austria.
Eva Trifina-MikoschTeaching Unit, Medizinische Universität Wien/Medical University Vienna, Vienna, Austria.
Medical University of Vienna · ATStadtkrankenhaus Schwabach · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hashimoto's thyroiditis (HT), also known as chronic lymphocytic thyroiditis, is a frequent disorder of the thyroid gland caused by autoimmune-trigged lymphocytic infiltration and destruction of the thyroid gland. With the progressive destruction of the organ, the thyroid gland shrinks in size, thus commonly leading to hypothyroidism. Therapy of HT is mainly focused on managing the thyroid dysfunction by oral substitution of L‑thyroxine. However, patients with HT often complain about a broad spectrum of symptoms, with some of them hardly explained by HT itself. Several other disorders are known to be associated with HT. The etiology of HT seems to be multifactorial, including environmental influences such as iodine supply, infections, and stress as triggers of immune modulation. In addition, also a genetic background based on changes of the human leukocyte antigen (HLA) status seems to be evident. The paper will provide an overview of diseases related to HT, including their correlation to certain HLA patterns. This presentation should give a broader view on HT-related disorders and facilitate detailed examination and management of patients with HT.

Indexed as

Hashimoto DiseaseHypothyroidismHLA AntigensHumansHLA AntigensAutoimmune disordersComorbidityDiagnosticsGeneticsThyroid

Identifiers

PMID34524590
PMCPMC9877058
OpenAlexW3200037020

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.