Evidence map›Paper›PMID 34524564›Full record

ArticleMagma (New York, N.Y.)2022

Automatic segmentation of whole-body adipose tissue from magnetic resonance fat fraction images based on machine learning.

Zhiming Wang, Chuanli Cheng, Hao Peng, Yulong Qi, Qian Wan, Hongyu Zhou, Shaocheng Qu, Dong Liang, Xin Liu, Hairong Zheng and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Magma (New York, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Zhiming Wang *College of Physical Science and Technology, Central China Normal University, Wuhan, China.
Chuanli Cheng *Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Hao PengPaul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Yulong QiRadiology Department, Peking University Shenzhen Hospital, Shenzhen, China.
Qian WanPaul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Hongyu ZhouPaul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Shaocheng QuCollege of Physical Science and Technology, Central China Normal University, Wuhan, China.
Dong LiangPaul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Xin LiuPaul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Hairong ZhengPaul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Chao ZouPaul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China. chao.zou@siat.ac.cn.ORCID http://orcid.org/0000-0002-6387-7809
Chinese Academy of Sciences · CNCentral China Normal University · CNPeking University Shenzhen Hospital · CN

Funding

China Postdoctoral Science Foundation 2019M650220Guangdong Grant 'Key Technologies for Treatment of Brain Disorders' 2018B030332001International Partnership Program of Chinese Academy of Sciences Grant 154144KYSB20180063National Natural Science Foundation of China 61901462National Natural Science Foundation of China 81801724Scientific Instrument Innovation Team of the Chinese Academy of Sciences GJJSTD20180002Shenzhen Double Chain Grant [2018]256Strategic Priority Research Program of Chinese Academy of Sciences XDB25000000
6 · The paper itself

Abstract

objectiveTo propose a fully automated algorithm, which is implemented to segment subcutaneous adipose tissue (SAT) and internal adipose tissue (IAT) from the total adipose tissue for whole-body fat distribution analysis using proton density fat fraction (PDFF) magnetic resonance images. MATERIALS AND

methodsAdipose tissue segmentation was implemented using the U-Net deep neural network model. All datasets were collected using a 3.0 T magnetic resonance imaging (MRI) scanner for whole-body scan of 20 volunteers covering from neck to knee with about 160 images for each volunteer. PDFF images were reconstructed based on chemical-shift-encoded fat-water imaging. After selecting the representative PDFF images (total 906 images), the manual labeling of the SAT area was used for model training (504 images), validation (168 images), and testing (234 images).

resultsThe automatic segmentation model was validated through three indices using the validation and test sets. The dice similarity coefficient, precision rate, and recall rate were 0.976 ± 0.048, 0.978 ± 0.048, and 0.978 ± 0.050, respectively, in both validation and test sets.

conclusionThe proposed algorithm can reliably and automatically segment SAT and IAT from whole-body MRI PDFF images. The proposed method provides a simple and automatic tool for whole-body fat distribution analysis to explore the relationship between fat deposition and metabolic-related chronic diseases.

Indexed as

Adipose TissueMagnetic Resonance ImagingHumansMachine LearningMagnetic Resonance SpectroscopyProtonsWhole Body ImagingProtonsInternal adipose tissueProton density fat fractionSubcutaneous adipose tissueU-Net deep neural networkWhole-body magnetic resonance imaging

Identifiers

PMID34524564
OpenAlexW3201498478

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.