Evidence map›Paper›PMID 34524519›Full record

SynthesisPediatric surgery international2022

Implementation and outcomes of enhanced recovery protocols in pediatric surgery: a systematic review and meta-analysis.

Arun Kumar Loganathan, Anita Shirley Joselyn, Malavika Babu, Susan Jehangir

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Pediatric surgery international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06981572 (Comparison of the Effectiveness of Implementing Modified ERAS Protocols vs. Standard Management in Pediatric Patients Undergoing Major Gastrointestinal Surgery), which is not on this map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06981572 nacompletednot on this mapstarted 2024, after this paper: background citation

Comparison of the Effectiveness of Implementing Modified ERAS Protocols vs. Standard Management in Pediatric Patients Undergoing Major Gastrointestinal Surgery

TypeinterventionalSponsorIndonesia UniversityRan2024 to 2025Enrolled82ConditionsSurgery, AnesthesiaArmsModified Enhanced Recovery After Surgery Protocol
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 56 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Arun Kumar LoganathanDepartment of Pediatric Surgery, Christian Medical College, Vellore, Tamil Nadu, 632002, India.
Anita Shirley JoselynDepartment of Anesthesia, Christian Medical College, Vellore, Tamil Nadu, India.
Malavika BabuDepartment of Biostatistics, Christian Medical College, Vellore, Tamil Nadu, India.
Susan JehangirDepartment of Pediatric Surgery, Christian Medical College, Vellore, Tamil Nadu, 632002, India. susanjehangir@cmcvellore.ac.in.ORCID http://orcid.org/0000-0002-9676-654X
Christian Medical College, Vellore · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis systematic review examines the feasibility and safety of implementing Enhanced recovery after Surgery (ERAS) protocols in children. STUDY

designA systematic search of Medline, PubMed, and the Cochrane library for papers describing ERAS implementation in children between January 2000 and January 2021. The systematic review was performed according to the PRISMA statement. The meta-analysis was done using R Software (Ver 4.0.2). p value of < 0.05 was considered statistically significant.

resultsSixteen studies, describing a total of 1723 patients, were included in the meta-analysis. An average of 15 (range 11-16) relevant components were implemented with an overall compliance close to 84%. The time to initiate feeds and reach full enteral nutrition was reduced in ERAS group with mean difference (MD) of - 21.20 h (95% CI - 22.80, - 19.59, p < 0.01), and - 2.20 days (95% CI - 2.72, - 1.71, p < 0.01), respectively. The use of opioids for postoperative analgesia was reduced with MD of -0.86 morphine equivalents mg/kg (95% CI - 1.40, - 0.32, p < 0.01). The length of hospital stay showed a significant reduction with MD of -2.54 days (95% CI - 2.94, - 2.13, p < 0.01). There was no difference in the complication and readmission rates between the groups.

conclusionERP implementation in pediatric perioperative care is a viable option in a variety of surgical settings. There is clear evidence of a decrease in hospital stay duration with no increase in complication or readmission rates. The length of hospital stay reduced in inverse proportion to the number of ERAS elements implemented. Parental satisfaction is increased by initiating enteral feeding early, minimizing catheter and drain use, and reducing opioid use.

Indexed as

Enhanced Recovery After SurgeryAnalgesics, OpioidChildClinical ProtocolsHumansLength of StayMorphinePerioperative CarePostoperative ComplicationsAnalgesics, OpioidMorphineChildrenEnhanced recoveryERASPaediatric surgery

Identifiers

PMID34524519
OpenAlexW3199275915

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.