Evidence map›Paper›PMID 34524514›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2021

Global alignment taking into account the cervical spine with odontoid hip axis angle (OD-HA).

Emmanuelle Ferrero, Pierre Guigui, Marc Khalifé, Robert Carlier, Antoine Feydy, Adrien Felter, Virginie Lafage, Wafa Skalli

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Spinopelvic measurements of sagittal balance with deep learning: systematic review and critical evaluation.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022
    Pooled it
  2. Review
  3. Observational
  4. Article
  5. Assessment of malalignment at early stage in adolescent idiopathic scoliosis: a longitudinal cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Article
  6. Article
  7. Assessment of dynamic balance during walking in patients with adult spinal deformity.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Emmanuelle FerreroDepartment of Orthopaedic Surgery, Hopital Européen Georges Pompidou, APHP, Paris V University, 20 rue Leblanc, 75015, Paris, France. emmanuelle.ferrero@aphp.fr.ORCID 0000-0003-3357-306X
Pierre GuiguiDepartment of Orthopaedic Surgery, Hopital Européen Georges Pompidou, APHP, Paris V University, 20 rue Leblanc, 75015, Paris, France.
Marc KhaliféDepartment of Orthopaedic Surgery, Hopital Européen Georges Pompidou, APHP, Paris V University, 20 rue Leblanc, 75015, Paris, France.
Robert CarlierDepartment of Radiology, Hopital de Garches, APHP, Garches, France.
Antoine FeydyDepartment of Radiology, Hopital Cochin, APHP, Paris V University, Paris, France.
Adrien FelterDepartment of Radiology, Hopital de Garches, APHP, Garches, France.
Virginie LafageSpineLab, Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, NY, USA.
Wafa SkalliLaboratoire de biomecanique Georges Charpak, Ecole nationale superieure des arts et metiers, 75013, Paris, France.
Université Paris Cité · FRArts et Métiers · FRHospital for Special Surgery · USInstitut de Biomécanique Humaine Georges Charpak · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGlobal alignment analysis is of upmost importance in adult spinal deformity patients (ASD). Numerous parameters exist in the literature to measure global alignment based upon C7 or T1. One common limitation of these parameters is that they neglect the cervical segment which is essential in spinal compensatory mechanisms and in horizontal gaze preservation. A recent stereoradiography analysis of asymptomatic subjects introduced a new 3D parameter (ODHA), defined as the angle between the vertical reference line and the line joining the odontoid tip (OD) to hip axis center (HA). Thus, the goal of this study was to analyze 3D global alignment of ASD patients using the new parameter odontoid hip axis angle and its relationship to other spinal parameters.

methodsIn this prospective study, 90 adult patients with lumbar scoliosis (Cobb > 20°) were included. All subjects underwent low dose biplanar X-rays with 3D spinal reconstructions. Based on published normative values of ODHA, we defined abnormally high value as mean ODHA of asymptomatic subject + 2SD (i.e., ODHA > 6.1°). Values of 3D radiographic parameters and ODI were compared between patients with ODHA > 6.1° and < 6.1°.

resultsMean ODHA was 5+/- 3.6° (0.4° to 18.6°). 22 patients had abnormally high ODHA. They were older than the 68 other patients (68+/- 9y vs 53+/- 14y, p = 0.001), without any significant difference in terms of sex, BMI and rate of rotatory subluxation (54% vs 62%, p = 0.06). However, coronal and sagittal deformity was more important in patients with abnormal ODHA (larger Cobb angle, coronal malalignment, pelvic tilt and lower lumbar lordosis). Patients with abnormal ODHA had significantly worst ODI (50+/- 23 vs 30+/- 18, p = 0.0005).

conclusionExtreme values of ODHA are observed in significantly older patients with significant functional impairment. In addition, in these patients with sagittal malalignment with loss of lumbar lordosis, who recruit compensatory mechanisms such as pelvic retroversion, the cervical area is also involved with a posture in cervical hyperlordosis to maintain the head over the pelvis. Thus, ODHA is an interesting parameter allowing a more comprehensive alignment measurement taking into account the mechanisms of compensation of the cervical spine to the pelvis.

Indexed as

LordosisOdontoid ProcessScoliosisAdultCervical VertebraeHumansProspective StudiesOdontoidSagittal alignmentSpinal balanceSpino-pelvic parametersStereoradiography

Identifiers

PMID34524514
OpenAlexW3199497715

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.