Evidence map›Paper›PMID 34524382›Full record

ArticleDental press journal of orthodontics2021

Supernumerary teeth in patients with cleft lip and palate: the tooth germs do not separate.

Alberto Consolaro, Maria Carolina Malta Medeiros, Dario Augusto Oliveira Miranda, Ingrid Araújo de Oliveira

Open access · diamondAbstract read
In one paragraph

Article in Dental press journal of orthodontics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Supernumerary teeth: A pictorial review and revised classification.Journal of oral biology and craniofacial research
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Alberto ConsolaroUniversidade de São Paulo, Faculdade de Odontologia de Bauru (Bauru/SP, Brazil).ORCID http://orcid.org/0000-0002-5902-5646
Maria Carolina Malta MedeirosOral and Maxillofacial Surgery department of the Cleft Lip and Palate Service of the "Hospital Infantil Dr. Juvêncio Matos" (São Luís/MA, Brazil).ORCID http://orcid.org/0000-0002-3659-1848
Dario Augusto Oliveira MirandaUniversidade Estadual de Feira de Santana, Departamento de Saúde (BA, Brazil).ORCID http://orcid.org/0000-0001-7648-6359
Ingrid Araújo de OliveiraOral and Maxillofacial Surgery department of the Cleft Lip and Palate Service of the "Hospital Infantil Dr. Juvêncio Matos" (São Luís/MA, Brazil).ORCID http://orcid.org/0000-0002-4663-6405
Hospital Infantil Albert Sabin · BRUniversidade de Ribeirão Preto · BRUniversidade Estadual de Feira de Santana · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSupernumerary teeth in cases of cleft lip and palate do not result from the division of normal germs before the formation of hard tissue. Deciduous and permanent teeth odontogenesis begins after the face has formed, either with or without the cleft. DISCUSSION: The most acceptable hypothesis to enable understanding of the presence of supernumerary teeth on one or both sides of the cleft palate is hyperactivity of the dental lamina in its walls. This hyperactivity, with the formation of more tooth germs, must be attributed to mediators and genes related to tooth formation, under strong influence of local epigenetic factors, whose developmental environment was affected by the presence of the cleft.

conclusionThe current concepts of embryology no longer support the fusion of embryonic processes for the formation of the face, but rather the leveling of the grooves between them. All human teeth have a dual embryonic origin, as they are composed of ectoderm and mesenchyme/ectomesenchyme, but this does not make it easy for them to be duplicated to form supernumerary teeth.

Indexed as

AnodontiaCleft LipCleft PalateTooth, SupernumeraryHumansTooth Germ

Identifiers

PMID34524382
PMCPMC8439185
OpenAlexW3201479893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.