Evidence map›Paper›PMID 34523993›Full record

ArticleMicrobiology spectrum2021

Tigecycline Heteroresistance and Resistance Mechanism in Clinical Isolates of Acinetobacter baumannii.

Jeongwoo Jo, Kwan Soo Ko

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.

  1. Pooled it
  2. Article
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  4. Article
  5. Review
  6. Biofilm Formation and the Pore ProteinsAntibiotics (Basel, Switzerland) · 2026
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  7. Review
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  9. Heteroresistance to amikacin inMicrobiology spectrum · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jeongwoo JoDepartment of Microbiology, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea.
Kwan Soo KoDepartment of Microbiology, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea.ORCID 0000-0002-0978-1937
Sungkyunkwan University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tigecycline is regarded as a last-resort treatment for multidrug-resistant Acinetobacter baumannii. However, tigecycline resistance in A. baumannii has increased worldwide. In this study, we investigated tigecycline heteroresistance in A. baumannii isolates from South Korea. Antibiotic susceptibility testing was performed on 323 nonduplicated A. baumannii isolates. Among 260 and 37 tigecycline-susceptible and -intermediate-resistant A. baumannii isolates, 146 (56.2%) and 22 (59.5%) isolates were identified as heteroresistant to tigecycline through a disk diffusion assay and population analysis profiling. For selected isolates, an

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsAnti-Bacterial AgentsBacterial ProteinsDisk Diffusion Antimicrobial TestsDrug Resistance, Multiple, BacterialHumansMembrane Transport ProteinsRibosomal ProteinsRNA, MessengerTigecyclineAdeA protein, Acinetobacter baumanniiAdeB protein, Acinetobacter baumanniiAdeC protein, Acinetobacter baumanniiAnti-Bacterial AgentsBacterial ProteinsMembrane Transport ProteinsRibosomal Proteinsribosomal protein S10RNA, MessengerTigecyclineAcinetobacter baumanniiefflux pumpheteroresistancetigecycline

Identifiers

PMID34523993
PMCPMC8557860
OpenAlexW3199979528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.