Evidence map›Paper›PMID 34523978›Full record

ArticlemSphere2021

B Cell Receptor Repertoire Analysis in Malaria-Naive and Malaria-Experienced Individuals Reveals Unique Characteristics of Atypical Memory B Cells.

Ashley E Braddom, Sebastiaan Bol, S Jake Gonzales, Raphael A Reyes, Kenneth Musinguzi, Felistas Nankya, Isaac Ssewanyana, Bryan Greenhouse, Evelien M Bunnik

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  8. Differences in phenotype between long-lived memory B cells againstbioRxiv : the preprint server for biology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Ashley E BraddomDepartment of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, The University of Texas Health Science Center at San Antoniogrid.267309.9, San Antonio, Texas, USA.
Sebastiaan BolDepartment of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, The University of Texas Health Science Center at San Antoniogrid.267309.9, San Antonio, Texas, USA.ORCID 0000-0002-3843-6657
S Jake GonzalesDepartment of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, The University of Texas Health Science Center at San Antoniogrid.267309.9, San Antonio, Texas, USA.
Raphael A ReyesDepartment of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, The University of Texas Health Science Center at San Antoniogrid.267309.9, San Antonio, Texas, USA.
Kenneth MusinguziInfectious Disease Research Collaboration, Kampala, Uganda.
Felistas NankyaInfectious Disease Research Collaboration, Kampala, Uganda.
Isaac SsewanyanaInfectious Disease Research Collaboration, Kampala, Uganda.
Bryan GreenhouseDepartment of Medicine, University of California San Francisco, San Francisco, California, USA.ORCID 0000-0003-0287-9111
Evelien M BunnikDepartment of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, The University of Texas Health Science Center at San Antoniogrid.267309.9, San Antonio, Texas, USA.ORCID 0000-0003-4003-3053
The University of Texas Health Science Center at San Antonio · USInfectious Diseases Research Collaboration · UGLondon School of Hygiene & Tropical Medicine · GBUniversity of California, San Francisco · US

Funding

TISSUE CULTURE---COREP30CA054174 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Robin Jean Leach · 1991 to 2026
$59.1M
Institute for Integration of Medicine & Science: A Partnership to Improve HealthUL1TR001120 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CLARK, ROBERT A, HARGREAVES, KENNETH M · 2013 to 2017
$16.5M
Defining conserved epitopes on polymorphic malaria antigensR01AI153425 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI BUNNIK, EVELIEN MARGARETHA · 2021 to 2025
$2.7M
NRSA Training Core (TL1)TL1TR002647 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CHUN, YONG-HEE PATRICIA, FREI, CHRISTOPHER R. · 2018 to 2022
$1.8M
Mentoring translational scientists in international infectious disease researchK24AI144048 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Bryan R Greenhouse · 2019 to 2026
$1.6M
High Throughput DNA Sequencer: Illumina HiSeq 3000 SequencerS10OD021805 · OD · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI LAI, ZHAO · 2016 to 2016
$600k
Graduate Research in Immunology Program (GRIP): To train graduate students for successful careers in academia, industry and governmentT32AI138944 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI ZHONG, GUANGMING · 2018 to 2022
$561k
NCATS NIH HHS TL1 TR002647NCATS NIH HHS UL1 TR001120NCI NIH HHS P30 CA054174NIAID NIH HHS K24 AI144048NIAID NIH HHS R01 AI153425NIAID NIH HHS T32 AI138944NIH HHS S10 OD021805
6 · The paper itself

Abstract

Malaria, caused by parasites of the

Indexed as

Immunologic MemoryAdultHumansImmunoglobulin GImmunoglobulin MMalaria, FalciparumMemory B CellsPlasmodium falciparumReceptors, Antigen, B-CellImmunoglobulin GImmunoglobulin MReceptors, Antigen, B-Celladaptive immune responseHCDR3humoral immunityIgMPlasmodiumsomatic hypermutation

Identifiers

PMID34523978
PMCPMC8550134
OpenAlexW3201357738

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.