ReviewArthritis & rheumatology (Hoboken, N.J.)2022
Myocardial Dysfunction and Heart Failure in Rheumatoid Arthritis.
Review in Arthritis & rheumatology (Hoboken, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Non-invasive Assessment of Rheumatoid Arthritis Cardiac Involvement: A Systematic Review of EchocardiographyCurrent medical imaging · 2025Pooled it
- Performance of the PREVENT heart failure risk score and correlation with microvascular dysfunction and coronary plaque burden in patients with rheumatoid arthritis.American journal of preventive cardiology · 2026Article
- Therapeutic Properties and Underlying Mechanisms of Traditional Chinese Medicine in Managing Rheumatoid Arthritis: An Integrative Review of Clinical and Molecular Findings.Phytotherapy research : PTR · 2026Review
- Curcumin improves myocardial redox status in an experimental model of rheumatoid arthritis.Molecular and cellular biochemistry · 2026Article
- Article
- GLP-1-based therapy and ICD-10-documented heart failure or respiratory failure events in non-diabetic adults with rheumatoid arthritis and obesity: a TriNetX federated cohort study.Clinical rheumatology · 2026Article
- Sex-specific traditional and disease-related risk factors for incident heart failure in patients with rheumatoid arthritis: a registry-based cohort study.Clinical rheumatology · 2026Article
- Heart Failure in Rheumatoid Arthritis: Epidemiology, Pathogenesis, Diagnosis, Treatment, and Emerging Insights-A Comprehensive Review.Medicina (Kaunas, Lithuania) · 2026Review
- Risk of cardiovascular disease associated with use of tumor necrosis factor inhibitors in ankylosing spondylitis.Journal of rheumatic diseases · 2026Article
- Myocardial fibrosis, the silent instigator of diastolic dysfunction in patients with rheumatoid arthritis.Physiological research · 2025Review
- Disease knowledge and quality of life among rheumatoid arthritis patients: a cross-sectional study.BMC rheumatology · 2025Article
- Risk of Incident Heart Failure and Heart Failure Subtypes in Patients With Rheumatoid Arthritis.Arthritis care & research · 2025Article
- From Joints to the Heart: An Integrated Perspective on Systemic Inflammation.Life (Basel, Switzerland) · 2025Review
- Evaluating the quality of care for heart failure hospitalizations in inflammatory arthritis - A population-based cohort study.American heart journal plus : cardiology research and practice · 2025Article
- Autoimmune inflammation as a key risk factor for heart failure with preserved ejection fraction: the different types of inflammation driving to HFpEF.Frontiers in medicine · 2025Review
- Heart Failure in Rheumatoid Arthritis: Clinical Implications.Current heart failure reports · 2024Review
- Cardiac MRI in Rheumatic Disease.Rheumatic diseases clinics of North America · 2024Review
- Association of congestive heart failure with mortality in individuals with rheumatoid arthritis: a cohort study.Clinical rheumatology · 2024Article
- Chronic β-adrenergic stress contributes to cardiomyopathy in rodents with collagen-induced arthritis.Acta pharmacologica Sinica · 2023Article
- Left ventricular remodeling in rheumatoid arthritis patients without clinical heart failure.Arthritis research & therapy · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Rheumatoid arthritis (RA) patients have almost twice the risk of heart failure (HF) as individuals without RA, even with adjustment for the presence of ischemic heart disease. Moreover, RA patients remain at a 2-fold higher risk of mortality from HF compared to non-RA patients. These observations suggest that RA-specific inflammatory pathways are significant contributors to this increased risk of HF. Herein we summarize the epidemiology of HF in RA patients, the differences in myocardial structure or function between RA patients and non-RA patients without clinical signs of HF, and data on the role of systemic and local inflammation in RA HF pathophysiology. We also discuss the impact of subduing inflammation through the use of RA disease-modifying therapies on HF and myocardial structure and function, emphasizing gaps in the literature and areas needing further research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.