Evidence map›Paper›PMID 34523808›Full record

ArticleOrthopaedic surgery2021

Mid- and Long-Term Follow-Up Efficacy Analysis of 3D-Printed Interbody Fusion Cages for Anterior Cervical Discectomy and Fusion.

Yuan-Zhang Jin, Bin Zhao, Xiang-Dong Lu, Yi-Bo Zhao, Xiao-Feng Zhao, Xiao-Nan Wang, Run-Tian Zhou, De-Tai Qi, Wen-Xuan Wang

Abstract read
In one paragraph

Article in Orthopaedic surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Article
  9. [3D-printed vertebral body in anterior spinal reconstruction after total spondylectomy for patients with cervical chordoma].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuan-Zhang JinDepartment of Orthopaedics, The Second Hospital of Shanxi Medical University, Taiyuan, China.
Bin ZhaoDepartment of Orthopaedics, The Second Hospital of Shanxi Medical University, Taiyuan, China.ORCID https://orcid.org/0000-0001-5360-6725
Xiang-Dong LuDepartment of Orthopaedics, The Second Hospital of Shanxi Medical University, Taiyuan, China.
Yi-Bo ZhaoDepartment of Orthopaedics, The Second Hospital of Shanxi Medical University, Taiyuan, China.
Xiao-Feng ZhaoDepartment of Orthopaedics, The Second Hospital of Shanxi Medical University, Taiyuan, China.
Xiao-Nan WangDepartment of Orthopaedics, The Second Hospital of Shanxi Medical University, Taiyuan, China.
Run-Tian ZhouDepartment of Orthopaedics, The Second Hospital of Shanxi Medical University, Taiyuan, China.
De-Tai QiDepartment of Orthopaedics, The Second Hospital of Shanxi Medical University, Taiyuan, China.
Wen-Xuan WangDepartment of Orthopaedics, The Second Hospital of Shanxi Medical University, Taiyuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the safety and stability of 3D-printed interbody fusion cages (3D-printed cages) in anterior cervical discectomy and fusion (ACDF) by investigating the mid- and long-term follow-up outcomes.

methodsIn this prospective study, the clinical data of 30 patients with CSM admitted to the Second Hospital of Shanxi Medical University from May 2012 to May 2014 were analyzed. The cohort comprised 18 males and 12 females with an average age of 60.22 ± 3.2 years. All patients were examined by X-ray, CT and MRI before the operation. A total of 30 cases of CSM were treated by ACDF with 3D printed cage implantation. Mid- and long-term follow-ups were performed after the surgery. Clinical efficacy was evaluated by comparing the JOA score, SF-36 score, change in neurological function, cervical curvature index (CCI), vertebral intervertebral height (VIH) and fusion rate before the operation, 6 months after the operation, and at the last follow-up.

resultsTwo of the 30 patients were lost to follow-up. The remaining patients were followed up for 48-76 (65.23 ± 3.54) months. The patients recovered satisfactorily with a significant clinical effect. The JOA score increased meanfully and the improvement rate was 89.4% at the final follow-up. The SF-36 score increased significantly from pre- to postoperatively. The height of the intervertebral space at the last follow-up was not statistically significantly different from that at 6 months after surgery (P > 0.05), showing that the height of the intervertebral space did not change much and the severity of cage subsidence (CS) decreased. The CCI improved from pre- to postoperatively. The CCI did not change much from the 6-month follow-up to the last follow-up. and the cage rate (CR) was 100% at the 6-month and last follow-ups. No severe complications, such as spinal cord injury, esophageal fistula, cerebrospinal fluid leakage, cervical hematoma or wound infection, occurred in any of the patients.

conclusionThe clinical and radiological results show that the application of 3D-printed cages in ACDF can significantly relieve symptoms. Moreover, 3D-printed cages can restore the curvature of the cervical spine, effectively maintain the intervertebral height for a long time, and prevent complications related to postoperative subsidence.

Indexed as

Printing, Three-DimensionalCervical VertebraeDiskectomyFemaleFollow-Up StudiesHumansMaleMiddle AgedProspective StudiesSpinal Cord DiseasesSpinal FusionTreatment Outcome3D printed cageACDFEfficacy analysisMid- and long-term follow-up

Identifiers

PMID34523808
PMCPMC8528997

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.