Evidence map›Paper›PMID 34523766›Full record

ArticleHead & neck2021

Assessment of pharyngeal motor function using a novel velopharyngeal squeeze maneuver and a novel endoscopic pharyngeal contraction grade scale in patients with dysphagia after radiotherapy for nasopharyngeal carcinoma.

Peter K M Ku, Alexander C Vlantis, Thomas S C Hui, David C M Yeung, Alex K F Lee, Thomas Law, Simon Y P Chan, Esther S M Poon, Sophie Y Y Lee, Becky Y T Chan and 13 more

Open access · hybridAbstract read
In one paragraph

Article in Head & neck, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Voice Meets Swallowing: A Scoping Review of Therapeutic Connections.American journal of speech-language pathology · 2025
    Article
  3. Article
  4. Article
  5. Article
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 3 institutions in 3 countries.

Peter K M KuDepartment of Otorhinolaryngology-Head and Neck Surgery, United Christian Hospital and Tseung Kwan O Hospital, Hong Kong.ORCID 0000-0002-2669-9126
Alexander C VlantisDepartment of Otorhinolaryngology-Head and Neck Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong.
Thomas S C HuiDepartment of Otorhinolaryngology-Head and Neck Surgery, United Christian Hospital and Tseung Kwan O Hospital, Hong Kong.
David C M YeungDepartment of Otorhinolaryngology-Head and Neck Surgery, United Christian Hospital and Tseung Kwan O Hospital, Hong Kong.
Alex K F LeeDepartment of Otorhinolaryngology-Head and Neck Surgery, United Christian Hospital and Tseung Kwan O Hospital, Hong Kong.
Thomas LawDepartment of Otorhinolaryngology-Head and Neck Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong.
Simon Y P ChanDepartment of Speech Therapy, Prince of Wales Hospital, Hong Kong.
Esther S M PoonDepartment of Speech Therapy, United Christian Hospital and Tseung Kwan O Hospital, Hong Kong.
Sophie Y Y LeeDepartment of Speech Therapy, United Christian Hospital and Tseung Kwan O Hospital, Hong Kong.
Becky Y T ChanDepartment of Speech Therapy, Prince of Wales Hospital, Hong Kong.
Twinky Y L CheungDepartment of Speech Therapy, Prince of Wales Hospital, Hong Kong.
Laurie Y W LokDepartment of Speech Therapy, Prince of Wales Hospital, Hong Kong.
Dennis T H ChengDepartment of Speech Therapy, Prince of Wales Hospital, Hong Kong.ORCID 0000-0003-3141-5105
Jade W S LiDepartment of Otorhinolaryngology-Head and Neck Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong.
Ken C W YamDepartment of Otorhinolaryngology-Head and Neck Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong.
Christina S M HoDepartment of Otorhinolaryngology-Head and Neck Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong.
Kristy P T FungDepartment of Otorhinolaryngology-Head and Neck Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong.
Coco S Y ChanDepartment of Otorhinolaryngology-Head and Neck Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong.
William H S WangDepartment of Otorhinolaryngology-Head and Neck Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong.
Jeffrey K T WongDepartment of Interventional Radiology and Organ Imaging, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong.
Victor AbdullahDepartment of Otorhinolaryngology-Head and Neck Surgery, United Christian Hospital and Tseung Kwan O Hospital, Hong Kong.
Andrew van HasseltDepartment of Otorhinolaryngology-Head and Neck Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong.
Michael C F TongDepartment of Otorhinolaryngology-Head and Neck Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong.
Chinese University of Hong Kong · HKUnited Christian Hospital · CNPrince of Wales Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo investigate a novel velopharyngeal squeeze maneuver (VPSM) and novel endoscopic pharyngeal contraction grade (EPCG) scale for the evaluation of pharyngeal motor function.

methodsDuring endoscopic examination of 77 post-irradiated nasopharyngeal carcinoma patients and control subjects, VPSM was rated and lateral pharyngeal wall movement graded with EPCG scale during swallowing. Pharyngeal constriction ratio (PCR) measured by videofluoroscopy was used for correlation.

resultsVPSM and EPCG scale showed almost perfect intra-rater and inter-rater reliability (Kappa: >0.90). VPSM was present in 61% of patients suggesting good pharyngeal motor function. VPSM was predictive of EPCG scale (Wald statistic = 29.99, p < 0.001). EPCG scale also correlated strongly with PCR (r: 0.812) and was predictive for aspiration (odds ratio: 22.14 [95% CI 5.01-97.89, p < 0.001]).

conclusionsVPSM and EPCG scale are two novel tools to assess pharyngeal motor function, and both correlate well with pharyngeal contractility and aspiration.

Indexed as

Deglutition DisordersNasopharyngeal NeoplasmsDeglutitionHumansNasopharyngeal CarcinomaPharynxReproducibility of Resultsdysphagiaendoscopynasopharyngeal carcinomapharyngeal motor functionpharyngeal squeeze

Identifiers

PMID34523766
PMCPMC9293071
OpenAlexW3201263457

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.