Evidence map›Paper›PMID 34523697›Full record

ArticleMolecular medicine reports2021

α‑rhamnrtin‑3‑α‑rhamnoside exerts anti‑inflammatory effects on lipopolysaccharide‑stimulated RAW264.7 cells by abrogating NF‑κB and activating the Nrf2 signaling pathway.

Jiang Tao Zhou, Kai Da Ren, Jing Hou, Jie Chen, Guan'e Yang

Open access · hybridAbstract read
In one paragraph

Article in Molecular medicine reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Investigating the Effect and Potential Mechanism of Rhamnetin 3-Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  4. Comprehensive analysis of protective effects ofAnimal cells and systems · 2025
    Article
  5. Protective Effects of Rhamnetin in Carbapenem-ResistantInternational journal of molecular sciences · 2023
    Article
  6. Antioxidants (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jiang Tao Zhou *Department of Chinese Medicine, School of Pharmaceutical Science, Shanxi Medical University, Jinzhong, Shanxi 030600, P.R. China.
Kai Da Ren *Department of Chinese Medicine, School of Pharmaceutical Science, Shanxi Medical University, Jinzhong, Shanxi 030600, P.R. China.
Jing HouDepartment of Chinese Medicine, School of Pharmaceutical Science, Shanxi Medical University, Jinzhong, Shanxi 030600, P.R. China.
Jie ChenDepartment of Chinese Medicine, School of Pharmaceutical Science, Shanxi Medical University, Jinzhong, Shanxi 030600, P.R. China.
Guan'e YangDepartment of Chinese Medicine, School of Pharmaceutical Science, Shanxi Medical University, Jinzhong, Shanxi 030600, P.R. China.
Shanxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

α‑rhamnrtin‑3‑α‑rhamnoside (ARR) is the principal compound extracted from

Indexed as

AnimalsAnti-Inflammatory AgentsChinaCyclooxygenase 2Heme Oxygenase-1LipopolysaccharidesLoranthaceaeMiceNF-E2-Related Factor 2NF-kappa BNitric OxideNitric Oxide Synthase Type IIPlant ExtractsQuercetinRAW 264.7 CellsSignal TransductionAnti-Inflammatory AgentsCyclooxygenase 2Heme Oxygenase-1LipopolysaccharidesNF-E2-Related Factor 2NF-kappa BNitric OxideNitric Oxide Synthase Type IIPlant ExtractsQuercetinrhamnetinTranscription Factor RelAinflammatory responseNF‑κB and nuclear factor‑erythroid 2‑related factor 2 signaling pathwayRAW264.7 cellsα‑rhamnrtin‑3‑α‑rhamnoside

Identifiers

PMID34523697
PMCPMC8456313
OpenAlexW3201284522

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.