Evidence map›Paper›PMID 34523695›Full record

ArticleMolecular medicine reports2021

PLAC1 is an independent predictor of poor survival, and promotes cell proliferation and invasion in cervical cancer.

Rujun Chen, Chan Sheng, Ruyue Ma, Liwen Zhang, Lina Yang, Yaping Chen

Open access · hybridAbstract read
In one paragraph

Article in Molecular medicine reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Transcriptomic Analysis ofInternational journal of molecular sciences · 2026
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  2. Transcriptomic Analysis ofbioRxiv : the preprint server for biology · 2026
    Article
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  9. Review
  10. Elevated INHBA Promotes Tumor Progression of Cervical Cancer.Technology in cancer research & treatment
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rujun Chen *Department of Gynaecology and Obstetrics, Shanghai Fifth People's Hospital, Fudan University, Shanghai 200240, P.R. China.
Chan Sheng *Department of Gynaecology and Obstetrics, Shanghai Fifth People's Hospital, Fudan University, Shanghai 200240, P.R. China.
Ruyue MaDepartment of Gynaecology and Obstetrics, Shanghai Fifth People's Hospital, Fudan University, Shanghai 200240, P.R. China.
Liwen ZhangDepartment of Gynaecology and Obstetrics, Shanghai Fifth People's Hospital, Fudan University, Shanghai 200240, P.R. China.
Lina YangDepartment of Gynaecology and Obstetrics, Shanghai Fifth People's Hospital, Fudan University, Shanghai 200240, P.R. China.
Yaping ChenDepartment of Gynaecology and Obstetrics, Shanghai Fifth People's Hospital, Fudan University, Shanghai 200240, P.R. China.
Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Placenta‑specific protein 1 (PLAC1) is inversely associated with survival in several types of cancer. However, whether PLAC1 is involved in the progression of cervical cancer (CC) remains to be elucidated. Therefore, the present study aimed to evaluate the prognostic role of PLAC1 in CC by determining the relationship between clinicopathological factors,

Indexed as

Cell Line, TumorCell ProliferationDatabases, GeneticEpithelial-Mesenchymal TransitionFemaleGene ExpressionGene Expression Regulation, NeoplasticHeLa CellsHumansKaplan-Meier EstimateNeoplasm InvasivenessPregnancy ProteinsPrognosisProportional Hazards ModelsSignal TransductionUterine Cervical NeoplasmsPLAC1 protein, humanPregnancy Proteinscervical cancerepithelial‑mesenchymal transitionplacenta‑specific protein 1prognosistumor metastasis

Identifiers

PMID34523695
PMCPMC8456314
OpenAlexW3199080343

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.