Evidence map›Paper›PMID 34523419›Full record

ArticleeLife2021

A novel bivalent chromatin associates with rapid induction of camalexin biosynthesis genes in response to a pathogen signal in

Kangmei Zhao, Deze Kong, Benjamin Jin, Christina D Smolke, Seung Yon Rhee

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Kangmei ZhaoCarnegie Institution for Science, Department of Plant Biology, Stanford, United States.ORCID 0000-0003-1472-4993
Deze KongDepartment of Bioengineering, Stanford University, Stanford, United States.ORCID 0000-0003-4334-5888
Benjamin JinCarnegie Institution for Science, Department of Plant Biology, Stanford, United States.
Christina D SmolkeDepartment of Bioengineering, Stanford University, Stanford, United States.ORCID 0000-0002-5449-8495
Seung Yon RheeCarnegie Institution for Science, Department of Plant Biology, Stanford, United States.ORCID 0000-0002-7572-4762
Carnegie Institution for Science · USBioengineering Center · RUChan Zuckerberg Initiative (United States) · US

Funding

An integrated pipeline for accelerated plant natural product discoveryU01GM110699 · NIGMS · STANFORD UNIVERSITY · PI SMOLKE, CHRISTINA D · 2015 to 2019
$4.5M
NIGMS NIH HHS U01 GM110699
6 · The paper itself

Abstract

Temporal dynamics of gene expression underpin responses to internal and environmental stimuli. In eukaryotes, regulation of gene induction includes changing chromatin states at target genes and recruiting the transcriptional machinery that includes transcription factors. As one of the most potent defense compounds in

Indexed as

ChromatinArabidopsisEpigenesis, GeneticGene Expression Regulation, PlantIndolesPhytoalexinsPlant DiseasesThiazolescamalexinChromatinIndolesPhytoalexinsThiazolesA. thalianabiotic stress responsebivalent chromatinplant biologyplant metabolismregulation of gene expression

Identifiers

PMID34523419
PMCPMC8547951
OpenAlexW3200249858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.