Evidence map›Paper›PMID 34523045›Full record

ArticleJournal of ophthalmic inflammation and infection2021

Combined endophthalmitis and orbital cellulitis in patients with corona virus disease (COVID-19).

Mohamed Farouk Sayed Othman Abdelkader, Ahmed Mohamed Kamal Elshafei, Mahmoud Mamdouh Nassar, Mostafa A Abu Elela, Raafat Mohyeldeen Abdelrahman Abdallah

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of ophthalmic inflammation and infection, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04456556 (Combined Endophthalmitis and Orbital Cellulitis in Patients With Novel Coronavirus Disease), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04456556 completednot on this map

Combined Endophthalmitis and Orbital Cellulitis in Patients With Novel Coronavirus Disease (COVID-19)

TypeobservationalSponsorMinia UniversityRan2020 to 2020Enrolled5ConditionsEndophthalmitis and Orbital Cellulitis
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mohamed Farouk Sayed Othman AbdelkaderOphthalmology Department, Faculty of Medicine, Minia University, El-Minia, 61519, Egypt. mohamed.osman@mu.edu.eg.ORCID http://orcid.org/0000-0002-2836-5314
Ahmed Mohamed Kamal ElshafeiOphthalmology Department, Faculty of Medicine, Minia University, El-Minia, 61519, Egypt.ORCID https://orcid.org/0000-0003-1394-2964
Mahmoud Mamdouh NassarOphthalmology Department, Faculty of Medicine, Minia University, El-Minia, 61519, Egypt.
Mostafa A Abu ElelaDepartment of Clinical pathology, Faculty of Medicine, Minia University, El-Minia, Egypt.
Raafat Mohyeldeen Abdelrahman AbdallahOphthalmology Department, Faculty of Medicine, Minia University, El-Minia, 61519, Egypt.ORCID https://orcid.org/0000-0002-5987-6889
Minia University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo document the presentation of unilateral combined endophthalmitis and orbital cellulitis in patients with COVID-19 infection and study their prognosis. PATIENTS AND

methodsThis interventional case series study included 9 patients referred to the Ophthalmology Department, Minia University Hospital with unilateral combined endophthalmitis and orbital cellulitis between April 2020 and March 2021. In addition to the COVID-19 work-up, all patients were subjected to full ophthalmological evaluation and managed according to their ophthalmic and systemic disease.

resultsThe patients were 5 females and 4 males. They had clinical, laboratory and imaging findings that confirmed COVID-19 infection. All patients had unilateral endophthalmitis with orbital cellulitis and profound visual loss in the affected eye. Three patients died due to respiratory failure, while 6 patients recovered systemically. The survived patients developed atrophia bulbi in 4 patients and in 2 patients, the globe retained normal size but with complete visual loss.

conclusionCombined endophthalmitis and orbital cellulitis can be one of the early presentations of patients with COVID-19 infection with poor visual prognosis.

trial registrationClinical registration: clinicaltrials.gov identifier: NCT04456556 .

Indexed as

COVID-19EndophthalmitisOrbital cellulitis

Identifiers

PMID34523045
PMCPMC8440116
OpenAlexW3199393246

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.