Evidence map›Paper›PMID 34522976›Full record

ArticleCurrent microbiology2021

Virulence Genes Profile and Antimicrobial Susceptibility of Community-Acquired Bacterial Urinary Tract Infections in a Brazilian Hospital.

Fernanda Morcatti Coura, Vitoria Marra de Souza Savini, Rafael Gariglio Clark Xavier, Carolina Pantuzza Ramos, Rodrigo Otávio Silveira Silva, Marcos Bryan Heinemann, Andrea Micke Moreno, Terezinha Knöbl, Elaine Maria Seles Dorneles, Dirceia Aparecida da Costa Custódio and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Current microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Fernanda Morcatti CouraInstituto Federal de Educação, Ciência e Tecnologia de Minas Gerais Campus Bambuí, IFMG, Faz. Varginha, Rodovia Bambuí/Medeiros, Km 05, Caixa-postal 05, Zona Rural, Bambuí, Minas Gerais, 38900-000, Brazil. fernanda.coura@ifmg.edu.br.ORCID http://orcid.org/0000-0003-2243-3125
Vitoria Marra de Souza SaviniInstituto Federal de Educação, Ciência e Tecnologia de Minas Gerais Campus Bambuí, IFMG, Faz. Varginha, Rodovia Bambuí/Medeiros, Km 05, Caixa-postal 05, Zona Rural, Bambuí, Minas Gerais, 38900-000, Brazil.
Rafael Gariglio Clark XavierEscola de Veterinária, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, UFMG, Av. Antônio Carlos, 6627, Belo Horizonte, Minas Gerais, CEP 30123-970, Brazil.
Carolina Pantuzza RamosEscola de Veterinária, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, UFMG, Av. Antônio Carlos, 6627, Belo Horizonte, Minas Gerais, CEP 30123-970, Brazil.
Rodrigo Otávio Silveira SilvaEscola de Veterinária, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, UFMG, Av. Antônio Carlos, 6627, Belo Horizonte, Minas Gerais, CEP 30123-970, Brazil.ORCID http://orcid.org/0000-0003-0074-2488
Marcos Bryan HeinemannFaculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, USP, Av. Prof Dr. Orlando Marques de Paiva, 87, São Paulo, São Paulo, CEP 05508-270, Brazil.ORCID http://orcid.org/0000-0001-6444-9788
Andrea Micke MorenoFaculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, USP, Av. Prof Dr. Orlando Marques de Paiva, 87, São Paulo, São Paulo, CEP 05508-270, Brazil.ORCID http://orcid.org/0000-0002-3290-566X
Terezinha KnöblFaculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, USP, Av. Prof Dr. Orlando Marques de Paiva, 87, São Paulo, São Paulo, CEP 05508-270, Brazil.
Elaine Maria Seles DornelesDepartamento de Medicina Veterinária, Universidade Federal de Lavras, UFLA, Av. Doutor Sylvio Menicucci, 1001, Campus Universitário, Lavras, Minas Gerais, 37200-900, Brazil.ORCID http://orcid.org/0000-0002-2753-1296
Dirceia Aparecida da Costa CustódioDepartamento de Medicina Veterinária, Universidade Federal de Lavras, UFLA, Av. Doutor Sylvio Menicucci, 1001, Campus Universitário, Lavras, Minas Gerais, 37200-900, Brazil.
Carine Rodrigues PereiraDepartamento de Medicina Veterinária, Universidade Federal de Lavras, UFLA, Av. Doutor Sylvio Menicucci, 1001, Campus Universitário, Lavras, Minas Gerais, 37200-900, Brazil.
Pedro Felipe Rodrigues E OliveiraDepartamento de Medicina Veterinária, Universidade Federal de Lavras, UFLA, Av. Doutor Sylvio Menicucci, 1001, Campus Universitário, Lavras, Minas Gerais, 37200-900, Brazil.
Amanda Bruno PulinelliFundação Hospitalar do Estado de Minas Gerais, FHEMIG, Fazenda da Lagoa, Zona Rural, Bambuí, Minas Gerais, CEP 38900-000, Brazil.
Universidade Federal de Lavras · BRUniversidade de São Paulo · BRUniversidade Federal de Minas Gerais · BRInstituto Federal de Educação, Ciência e Tecnologia de Minas Gerais · BRFundação Hospitalar do Estado de Minas Gerais · BR

Funding

IFMG Edital 65/2018
6 · The paper itself

Abstract

Urinary tract infections (UTI) are one of the most common diseases worldwide and Escherichia coli is the most common causative bacteria. Empirical treatment is challenging due to antimicrobial or multidrug-resistance. The aims of this study were to determine the uropathogens and their antimicrobial susceptibility profile, as well as to identify the phylogroups and virulence genes of E. coli strains, associated with community-acquired UTI in outpatients admitted at a Brazilian Hospital in southeast Brazil. In total, 47 bacterial strains were isolated from 47 patients, 44 women and 2 men (no gender record from one patient). The age of the patients whose urine culture were positive varied from 0 (less than one month) to 104 years. Most of the isolates were E. coli (41/47), followed by Klebsiella pneumoniae (2/47), Klebsiella variicola/Klebsiella aerogenes (1/47), Pseudomonas aeruginosa (1/47), Proteus mirabilis (1/47), and Citrobacter koseri (1/47). Most E. coli strains were classified as phylogroup B2 (15/41 = 36.59%) and B1 (12/41 = 29.27%) and the most common virulence genes among E. coli strains were fimH (31/41 = 75.61%), iutA (21/41 = 51.22%), and tratT (16/41 = 39.02%). Among the E. coli strains, 59% were multidrug-resistance and strains that were ampicillin, sulfamethoxazole/trimethoprim, or tetracycline-resistant exhibited more chance to be multidrug-resistance, with an odds ratio of 100.00 [95% confidence interval (CI) 9.44-1059.26], 22.50 (95% CI 3.95-128.30), and 12.83 (95% CI 2.68-61.45), respectively. Our results showed that E. coli was the main etiological agent identified and demonstrated high frequency of multidrug-resistance and virulence factors in bacterial strains isolated from UTIs.

Indexed as

Escherichia coli InfectionsUrinary Tract InfectionsAnti-Bacterial AgentsBrazilEscherichia coliFemaleHospitalsHumansKlebsiellaMaleMicrobial Sensitivity TestsVirulenceAnti-Bacterial Agents

Identifiers

PMID34522976
OpenAlexW3199094373

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.