Evidence map›Paper›PMID 34522877›Full record

ArticleJournal of translational autoimmunity2021

Causal risk and protective factors in rheumatoid arthritis: A genetic update.

M Arleevskaya, E Takha, S Petrov, G Kazarian, A Novikov, R Larionova, A Valeeva, E Shuralev, M Mukminov, C Bost and 1 more

Abstract read
In one paragraph

Article in Journal of translational autoimmunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Anti-Frontiers in medicine · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Anti-Citrullinated Peptide Antibodies Control OralInternational journal of molecular sciences · 2022
    Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

M ArleevskayaCentral Research Laboratory, Kazan State Medical Academy, Kazan, Russia.
E TakhaCentral Research Laboratory, Kazan State Medical Academy, Kazan, Russia.
S PetrovCentral Research Laboratory, Kazan State Medical Academy, Kazan, Russia.
G KazarianCentral Research Laboratory, Kazan State Medical Academy, Kazan, Russia.
A NovikovSobolev Institute of Mathematics, Siberian Branch of Russian Academy of Science, Russia.
R LarionovaCentral Research Laboratory, Kazan State Medical Academy, Kazan, Russia.
A ValeevaCentral Research Laboratory, Kazan State Medical Academy, Kazan, Russia.
E ShuralevCentral Research Laboratory, Kazan State Medical Academy, Kazan, Russia.
M MukminovCentral Research Laboratory, Kazan State Medical Academy, Kazan, Russia.
C BostCHU Toulouse, INSERM U1291, CNRS U5051, University Toulouse III, Toulouse, France.
Y RenaudineauCentral Research Laboratory, Kazan State Medical Academy, Kazan, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The characterization of risk and protective factors in complex diseases such as rheumatoid arthritis (RA) has evolved from epidemiological studies, which test association, to the use of Mendelian randomization approaches, which test direct relationships. Indeed, direct associations with the mucosal origin of RA are retrieved with periodontal disease (

Indexed as

InflammationMendelian's randomizationRheumatoid arthritisRisk factorsSoluble IL-6 receptor

Identifiers

PMID34522877
PMCPMC8424591

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.