Evidence map›Paper›PMID 34522820›Full record

ArticleThe South African journal of physiotherapy2021

Inspiratory muscle training in children and adolescents living with neuromuscular diseases: A pre-experimental study.

Anri Human, Brenda M Morrow

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in The South African journal of physiotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05632666 naunknown statusnot on this map

Respiratory Muscle Training in Patients With Spinal Muscular Atrophy (SMA).

TypeinterventionalSponsorUMC UtrechtRan2021 to 2023Enrolled30ConditionsSpinal Muscular AtrophyArmsInspiratory and expiratory muscle training at a therapeutic intensity, Inspiratory and expiratory muscle training at a non-therapeutic intensity
NCT05951790 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Efficacy and Feasibility of Inspiratory Muscle Training (IMT) in Adult People With Pompe Disease: a Multicentre, Cross-over Randomized Control Trial (RCT)

TypeinterventionalSponsorFondazione Don Carlo Gnocchi ETSRan2023 to 2024Enrolled20ConditionsGlycogen Storage Disease Type II, Pompe Disease (Late-onset)ArmsInspiratory Muscle Training (IMT), Inspiratory Muscle Training (IMT) + Air Stacking
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Inspiratory muscle training in children with neuromuscular disorders.The South African journal of physiotherapy · 2024
    Trial
  5. Article
  6. Article
  7. Pulmonary Involvement in Neuromuscular Diseases: A Review.Iranian journal of child neurology · 2023
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Anri HumanDepartment of Physiotherapy, Faculty of Healthcare Sciences, Sefako Makgatho Health Sciences University, Garankuwa, Pretoria, South Africa.ORCID https://orcid.org/0000-0002-5960-6256
Brenda M MorrowDepartment of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, University of Cape Town, Rondebosch, South Africa.ORCID https://orcid.org/0000-0001-5193-918X
University of Cape Town · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChildren with neuromuscular diseases (NMD) are at risk of morbidity and mortality because of progressive respiratory muscle weakness and ineffective cough. Inspiratory muscle training (IMT) aims to preserve or improve respiratory muscle strength, thereby reducing morbidity and improving health-related quality of life (HRQoL).

objectivesTo describe the safety and feasibility of a 6-week IMT programme using an electronic threshold device (Powerbreathe®). Any adverse events and changes in functional ability, spirometry, peak expiratory cough flow (PECF), inspiratory muscle strength and HRQoL (Pediatric Quality of Life [PedsQL]) were recorded.

methodsA convenience sample of eight participants (

resultsThere were significant pre- to post-intervention improvements in upper limb function and coordination (

conclusionInspiratory muscle training (at an intensity of 30% Pimax) appears safe, feasible and acceptable, in a small sample of children and adolescents with NMD and was associated with improved inspiratory muscle strength, PIF and upper limb function and coordination. CLINICAL IMPLICATIONS: Larger, longer-term randomised controlled trials are warranted to confirm the safety and efficacy of IMT as an adjunct respiratory management strategy in children with NMD.

Indexed as

childreninspiratory muscle strengthinspiratory muscle trainingneuromuscular diseasepulmonary function

Identifiers

PMID34522820
PMCPMC8424756
OpenAlexW3198001008

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.