Evidence map›Paper›PMID 34522697›Full record

ArticleRobotic surgery (Auckland)2021

Introducer Design Concepts for an Epicardial Parallel Wire Robot.

Aman Ladak, Deepika Dixit, Michael S Halbreiner, Michael J Passineau, Srinivas Murali, Cameron N Riviere

Abstract read
In one paragraph

Article in Robotic surgery (Auckland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Development of a Flexible Parallel Wire Robot for Epicardial Interventions.The international journal of medical robotics + computer assisted surgery : MRCAS · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aman LadakThe Robotics Institute, Carnegie Mellon University, Pittsburgh, PA, USA.
Deepika DixitThe Robotics Institute, Carnegie Mellon University, Pittsburgh, PA, USA.
Michael S HalbreinerCardiovascular Institute, Allegheny Health Network, Pittsburgh, PA, USA.
Michael J PassineauCardiovascular Institute, Allegheny Health Network, Pittsburgh, PA, USA.
Srinivas MuraliCardiovascular Institute, Allegheny Health Network, Pittsburgh, PA, USA.
Cameron N RiviereThe Robotics Institute, Carnegie Mellon University, Pittsburgh, PA, USA.ORCID 0000-0002-6749-3140

Funding

Biodegradable, Thermoresponsive Hydrogels to Treat Ischemic CardiomyopathyR01HL105911 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WAGNER, WILLIAM R · 2011 to 2015
$1.8M
NHLBI NIH HHS R01 HL105911
6 · The paper itself

Abstract

backgroundCardiac gene therapies lack effective delivery methods to the myocardium. While direct injection has demonstrated success over a small region, homogenous gene expression requires many injections over a large area. To address this need, we developed a minimally invasive flexible parallel wire robot for epicardial interventions. To accurately deploy it onto the beating heart, an introducer mechanism is required.

methodsTwo mechanisms are presented. Assessment of the robot's positioning, procedure time, and pericardium insertion forces are performed on an artificial beating heart.

resultsSuccessful positioning was demonstrated. The mean procedure time was 230 ± 7 seconds for mechanism I and 259 ± 4 seconds for mechanism II. The mean pericardium insertion force was 2.2 ± 0.4 N anteriorly and 3.1 ± 0.4 N posteriorly.

conclusionIntroducer mechanisms demonstrate feasibility in facilitating the robot's deployment on the epicardium. Pericardium insertion forces and procedure times are consistent and reasonable.

Indexed as

beating-heart surgeryepicardial interventionrobotic surgerysubxiphoid access

Identifiers

PMID34522697
PMCPMC8435034

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.