Evidence map›Paper›PMID 34522639›Full record

ArticleJournal of traditional and complementary medicine2021

Wound healing activity of the hydroethanolic extract of the leaves of

Francyelle Borges Rosa de Moura, Bruno Antonio Ferreira, Simone Ramos Deconte, Breno Costa Landim, Allisson Benatti Justino, Andrea Aparecida de Aro, Foued Salmen Espindola, Rodney Alexandre Ferreira Rodrigues, Daniele Lisboa Ribeiro, Fernanda de Assis Araújo and 1 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of traditional and complementary medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Ointment-Based Combination ofPharmaceuticals (Basel, Switzerland) · 2022
    Article
  6. Spray film-forming system formulation ofJournal of advanced pharmaceutical technology & research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Francyelle Borges Rosa de MouraInstitute of Biomedical Sciences, Federal University of Uberlândia, Avenue Pará 1720, zip code 38400-902, Uberlândia, MG, Brazil.
Bruno Antonio FerreiraInstitute of Biomedical Sciences, Federal University of Uberlândia, Avenue Pará 1720, zip code 38400-902, Uberlândia, MG, Brazil.
Simone Ramos DeconteInstitute of Biomedical Sciences, Federal University of Uberlândia, Avenue Pará 1720, zip code 38400-902, Uberlândia, MG, Brazil.
Breno Costa LandimInstitute of Biomedical Sciences, Federal University of Uberlândia, Avenue Pará 1720, zip code 38400-902, Uberlândia, MG, Brazil.
Allisson Benatti JustinoInstitute of Biotechnology, Federal University of Uberlândia, Street Acre 1004, zip code 38405-319, Uberlândia, MG, Brazil.
Andrea Aparecida de AroInstitute of Biology, State University of Campinas, Street Monteiro Lobato, 255, zip code 13083-862, Campinas, SP, Brazil.
Foued Salmen EspindolaInstitute of Biotechnology, Federal University of Uberlândia, Street Acre 1004, zip code 38405-319, Uberlândia, MG, Brazil.
Rodney Alexandre Ferreira RodriguesMultidisciplinary Center of Chemical, Biological and Agricultural Research, State University of Campinas, Street Alexandre Cazelatto 999, zip code 13148-218, Paulínia, SP, Brazil.
Daniele Lisboa RibeiroInstitute of Biomedical Sciences, Federal University of Uberlândia, Avenue Pará 1720, zip code 38400-902, Uberlândia, MG, Brazil.
Fernanda de Assis AraújoInstitute of Biomedical Sciences, Federal University of Uberlândia, Avenue Pará 1720, zip code 38400-902, Uberlândia, MG, Brazil.
Tatiana Carla TomiossoInstitute of Biomedical Sciences, Federal University of Uberlândia, Avenue Pará 1720, zip code 38400-902, Uberlândia, MG, Brazil.
Universidade Federal de Uberlândia · BRUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimEXPERIMENTAL PROCEDURE: Wounds were induced on mice and treated with the extract. The treatment was performed daily, until day 7 after wound induction. Wound closure was measured and the features of the repaired tissue were investigated, including mast cell quantification, neutrophil and macrophage activities, collagen deposition, angiogenesis, and pro-metalloproteases and metalloproteases 2 and 9 activity (pro-MMPs and MMPs). RESULTS AND

conclusionThe

Indexed as

CelastraceaeCollagenHb, HemoglobinInflammationMedicinal plantsMiHE, Maytenus ilicifolia hydroethanolic extractMMP2, metalloprotease 2 activeMMP9, metalloprotease 9 activeMPO, myeloperoxidaseNAG, N-acetyl-beta-d-glucosaminidasePolyphenolPro-MMP2, pro-metalloprotease 2Pro-MMP9, pro-metalloprotesase 9

Identifiers

PMID34522639
PMCPMC8427480
OpenAlexW3151427833

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.