Evidence map›Paper›PMID 34522633›Full record

ArticleJournal of traditional and complementary medicine2021

Puxvadee Chaikul, Mayuree Kanlayavattanakul, Jariya Somkumnerd, Nattaya Lourith

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Journal of traditional and complementary medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05986799 (A Randomized, Controlled Trial of Efficacy of Amway Herbal Drink to Improve Skin Anti-aging), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05986799 naunknown statusnot on this mapstarted 2023, after this paper: background citation

A Randomized, Controlled Trial of Efficacy of Amway Herbal Drink to Improve Skin Anti-aging

TypeinterventionalSponsorAmway (China) R&D CenterRan2023 to 2023Enrolled30ConditionsSkin Laxity, Skin LinesArmsAmway Herbal Drink, Placebo Drink
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
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  9. Protective effect and mechanism research of Phyllanthus emblica Linn. fruit extract on UV-induced photodamage in keratinocytes.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2023
    Article
  10. Article
  11. Characterization and ex vivo evaluation of excised skin samples as substitutes for human dermal barrier in pharmaceutical and dermatological studies.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2022
    Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Puxvadee ChaikulSchool of Cosmetic Science, Mae Fah Luang University, Chiang Rai, 57100, Thailand.
Mayuree KanlayavattanakulSchool of Cosmetic Science, Mae Fah Luang University, Chiang Rai, 57100, Thailand.
Jariya SomkumnerdSchool of Cosmetic Science, Mae Fah Luang University, Chiang Rai, 57100, Thailand.
Nattaya LourithSchool of Cosmetic Science, Mae Fah Luang University, Chiang Rai, 57100, Thailand.
Mae Fah Luang University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimSkin aging influences the changes in skin, including skin dryness, wrinkle, and irregular pigmentation. Amla ( EXPERIMENTAL PROCEDURE: Amla branches were standardized the phenolic acids. The extract was investigated anti-skin aging activities, including antioxidant, anti-tyrosinase, anti-melanogenesis, and matrix metalloproteinase-2 inhibitory assays. Topical gel containing extract was prepared and evaluated the skin irritation by a single closed patch test. Randomized, double-blind, placebo-control study was performed in 20 volunteers for 84 consecutive days. The tested skin was evaluated by Chromameter® CR 400, Dermalab® USB, Mexameter® MX 18, Corneometer® CM 825, and Visioscan® VC 98.

resultsAmla branch extract, a dark brown powder, consisted a variety of phenolic acids, mainly sinapic and ferulic acids. The extract exhibited the potent antioxidant and tyrosinase inhibitory activities

conclusionThe study results suggested that amla branch is a rich source of bioactive compounds and can be a potential ingredient for utilization in anti-skin aging products.

Indexed as

Anti-Skin agingCellular assayClinical trialIn vitro assayPhenolic acids

Identifiers

PMID34522633
PMCPMC8427479
OpenAlexW3127706978

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.