Evidence map›Paper›PMID 34522579›Full record

ReviewActa pharmaceutica Sinica. B2021

Cell membrane-derived vesicles for delivery of therapeutic agents.

Quoc-Viet Le, Jaiwoo Lee, Hobin Lee, Gayong Shim, Yu-Kyoung Oh

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Acta pharmaceutica Sinica. B, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed.

  1. Review
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  15. Bioactive materials · 2025
    Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Quoc-Viet LeCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Republic of Korea.
Jaiwoo LeeCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Republic of Korea.
Hobin LeeCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Republic of Korea.
Gayong ShimSchool of Systems Biomedical Science, Soongsil University, Seoul 06978, Republic of Korea.
Yu-Kyoung OhCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell membranes have recently emerged as a new source of materials for molecular delivery systems. Cell membranes have been extruded or sonicated to make nanoscale vesicles. Unlike synthetic lipid or polymeric nanoparticles, cell membrane-derived vesicles have a unique multicomponent feature, comprising lipids, proteins, and carbohydrates. Because cell membrane-derived vesicles contain the intrinsic functionalities and signaling networks of their parent cells, they can overcome various obstacles encountered

Indexed as

Blood cellsCancer cellsCAR-T, chimeric antigen receptor-engineered T cellCell membrane-derived vesiclesCRISPR, clustered regularly interspaced short palindromic repeatsCXCR4, C-X-C chemokine receptor type 4DC, dendritic cellDrug-delivery systemsImmune cellsManufacturingMembrane engineeringNF-κB, nuclear factor kappa BNIR, near infraredPEG, polyethylene glycolPLGA, poly(lactic-co-glycolic acid)RBC, red blood cellStem cellsTCR, T-cell receptorTRAIL, tumor necrosis factor-related apoptosis-inducing ligand

Identifiers

PMID34522579
PMCPMC8424219

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.