ArticleCureus2021
Parkinsonism in a Patient With Metal on Metal Total Hip Replacement Related Elevated Serum Heavy Metal Levels.
Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed, 3 citations in OpenAlex.
- Cerebrovascular accidents association between serum trace elements and toxic metals level, a case-control study.PloS one · 2025Article
- Current Insights into Plausible Mechanisms of Chromium (VI) Neurotoxicity in the Brain and Future Perspectives.Medical journal of the Islamic Republic of Iran · 2025Article
- Systemic Cobalt Toxicity Secondary to Metal-on-Metal Prosthetic Hip Replacement: a Case Report.Journal of general internal medicine · 2024Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heavy metal toxicity accounts for a rare minority of parkinsonian presentations. It is established that metal on metal total hip replacements can elevate serum cobalt and chromium levels. Here, we present an atypical parkinsonism presentation in a patient with metal on metal total hip replacement related heavy metal exposure, a picture complicated by a previous cerebral vascular accident involving the right lentiform nucleus. Initial work-up included MRI brain and dopamine transporter uptake imaging. A follow-up consultation revealed progressing parkinsonism. This case presentation reports the first parkinsonism presentation associated with metal on metal total hip replacement related heavy metal toxicity.
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Registered trials
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