Evidence map›Paper›PMID 34522492›Full record

ArticleCureus2021

An Adrenocortical Carcinoma Evolving After Nine Years of Latency From a Small Adrenal Incidentaloma.

Harpreet S Kohli, Sukesh Manthri, Shikha Jain, Rahul Kashyap, Sheng Chen, Thoyaja Koritala, Aysun Tekin, Ramesh Adhikari, Raghavendra Tirupathi, Aram Barbaryan and 11 more

Abstract readCase Reports
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Harpreet S KohliDepartment of Hospital Medicine, Saint Vincent Hospital, Erie, USA.
Sukesh ManthriDepartment of Oncology, Mary Bird Perkins Cancer Center, Houma, USA.
Shikha JainDepartment of Internal Medicine, MVJ Medical College, Bengaluru, IND.
Rahul KashyapDepartment of Anesthesiology and Critical Care Medicine, Mayo Clinic, Rochester, USA.
Sheng ChenDepartment of Pathology, Memorial Medical Center, Springfield, USA.
Thoyaja KoritalaDepartment of Internal Medicine, Mayo Clinic Health System, Mankato, USA.
Aysun TekinDepartment of Anesthesiology and Critical Care Medicine, Mayo Clinic, Rochester, USA.
Ramesh AdhikariDepartment of Hospital Medicine, Franciscan Health, Lafayette, USA.
Raghavendra TirupathiDepartment of Internal Medicine, Keystone Health, Chambersburg, USA.
Aram BarbaryanDepartment of Internal Medicine, University of Kansas Health System, Kansas City, USA.
Simon ZecDepartment of Critical Care Medicine, Mayo Clinic, Rochester, USA.
Hanyin WangDepartment of Hospital Medicine, Mayo Clinic Health System, Mankato, USA.
Stephanie WelleDepartment of Cardiology, Mayo Clinic Health System, Mankato, USA.
Pavan DevulapallyNephrology, Methodist Hospital, San Antonio, USA.
Mack SheratonEmergency Medicine, Johns Hopkins University, Baltimore, USA.
Manpreet KaurDepartment of Medicine, Drishti Advanced Eye and Diabetes Care Center, Patiala, IND.
Vishwanath PattanDivision of Endocrinology, Wyoming Medical Center, Casper, USA.
Chaitanya K MamillapalliDivision of Endocrinology, Southern Illinois University School of Medicine, Springfield, USA.
Salim R SuraniDepartment of Pulmonary and Critical Care Medicine, Texas A&M University, Corpus Christi, USA.
Syed Anjum KhanDepartment of Critical Care Medicine, Mayo Clinic Health System, Mankato, USA.
Nitesh K JainDepartment of Critical Care Medicine, Mayo Clinic Health System, Mankato, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adrenal incidentalomas (AIs) are common incidental findings in medical practice with clinical significance. Although most AIs are nonsecretory and nonmalignant, they require a short course of follow-up over one to two years to rule out malignancy or hormonal secretion according to clinical practice guidelines. However, this can result in some adrenocortical carcinomas (ACCs) being missed if they transform at a later stage or evolve slowly. Here, we report one such case of an AI, which although remained indolent, eventually transformed into an ACC many years after the initial detection.

Indexed as

adrenal carcinomaadrenal diseaseadrenal disordersadrenal incidentalomaadrenal pheochromocytomaadrenal surgerybenign adrenal tumorclinical guidelinesindeterminate adrenal nodulesecretory tumors of adrenal gland

Identifiers

PMID34522492
PMCPMC8425154

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.