Evidence map›Paper›PMID 34522444›Full record

ArticleImmune network2021

Tumor-Infiltrating Neutrophils and Non-Classical Monocytes May Be Potential Therapeutic Targets for HER2

Juhee Jeong, Duk Ki Kim, Ji-Hyeon Park, Do Joong Park, Hyuk-Joon Lee, Han-Kwang Yang, Seong-Ho Kong, Keehoon Jung

Open access · diamondAbstract read
In one paragraph

Article in Immune network, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Juhee JeongDepartment of Anatomy and Cell Biology, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID https://orcid.org/0000-0003-4732-147X
Duk Ki KimDepartment of Anatomy and Cell Biology, Seoul National University College of Medicine, Seoul 03080, Korea.
Ji-Hyeon ParkDepartment of Surgery, Seoul National University Hospital, Seoul 03080, Korea.ORCID https://orcid.org/0000-0002-6811-8895
Do Joong ParkDepartment of Surgery, Seoul National University Hospital, Seoul 03080, Korea.ORCID https://orcid.org/0000-0001-9644-6127
Hyuk-Joon LeeDepartment of Surgery, Seoul National University Hospital, Seoul 03080, Korea.ORCID https://orcid.org/0000-0002-9530-647X
Han-Kwang YangDepartment of Surgery, Seoul National University Hospital, Seoul 03080, Korea.
Seong-Ho KongDepartment of Surgery, Seoul National University Hospital, Seoul 03080, Korea.
Keehoon JungDepartment of Anatomy and Cell Biology, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID https://orcid.org/0000-0002-2199-5292
Seoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer (GC) is the fourth most common cause of cancer-related death globally. The classification of advanced GC (AGC) according to molecular features has recently led to effective personalized cancer therapy for some patients. Specifically, AGC patients whose tumor cells express high levels of human epidermal growth factor receptor 2 (HER2) can now benefit from trastuzumab, a humanized monoclonal Ab that targets HER2. However, patients with HER2

Indexed as

Gastric cancerImmunotherapyNeutrophilsNon-classical monocytesTumor microenvironment

Identifiers

PMID34522444
PMCPMC8410991
OpenAlexW3198548753

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.