Evidence map›Paper›PMID 34522438›Full record

ArticleImmune network2021

Interactions between NCR

Jongho Ham, Jihyun Kim, Sungmi Choi, Jaehyun Park, Min-Gyung Baek, Young-Chan Kim, Kyoung-Hee Sohn, Sang-Heon Cho, Siyoung Yang, Yong-Soo Bae and 5 more

Open access · diamondAbstract read
In one paragraph

Article in Immune network, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Winds of change a tale of: asthma and microbiome.Frontiers in microbiology · 2023
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Jongho HamLaboratory of Mucosal Immunology, Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-9423-2053
Jihyun KimLaboratory of Mucosal Immunology, Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-1222-0345
Sungmi ChoiInterdisciplinary Program in Precision Public Health, Korea University, Seoul, Korea.ORCID https://orcid.org/0000-0003-4658-9917
Jaehyun ParkInterdisciplinary Program in Bioinformatics, Seoul National University College of Natural Sciences, Seoul, Korea.ORCID https://orcid.org/0000-0003-2900-8340
Min-Gyung BaekInterdisciplinary Program in Precision Public Health, Korea University, Seoul, Korea.ORCID https://orcid.org/0000-0001-6319-5405
Young-Chan KimDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-6726-5957
Kyoung-Hee SohnDepartment of Internal Medicine, Kyung Hee University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0001-8407-8080
Sang-Heon ChoInstitute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-7644-6469
Siyoung YangDepartment of Pharmacology, Ajou University School of Medicine, Suwon, Korea.ORCID https://orcid.org/0000-0002-6374-0140
Yong-Soo BaeCenter for Immune Research on Non-Lymphoid Organ (CIRNO), Sungkyunkwan University, Suwon, Korea.ORCID https://orcid.org/0000-0002-2233-9449
Doo Hyun ChungDepartment of Biomedical Sciences, BK21 Plus Biomedical Science Project, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-9948-8485
Sungho WonDepartment of Public Health Sciences, Seoul National University, Seoul, Korea.ORCID https://orcid.org/0000-0001-5751-5089
Hana YiInterdisciplinary Program in Precision Public Health, Korea University, Seoul, Korea.ORCID https://orcid.org/0000-0002-4910-122X
Hye Ryun KangInstitute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-2317-4201
Hye Young KimLaboratory of Mucosal Immunology, Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-5978-512X
Seoul National University · KRKorea University · KRSeoul National University Hospital · KRAjou University · KRKyung Hee University Dental Hospital · KRSungkyunkwan University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asthma is a heterogeneous disease whose development is shaped by a variety of environmental and genetic factors. While several recent studies suggest that microbial dysbiosis in the gut may promote asthma, little is known about the relationship between the recently discovered lung microbiome and asthma. Innate lymphoid cells (ILCs) have also been shown recently to participate in asthma. To investigate the relationship between the lung microbiome, ILCs, and asthma, we recruited 23 healthy controls (HC), 42 patients with non-severe asthma, and 32 patients with severe asthma. Flow cytometry analysis showed severe asthma associated with fewer natural cytotoxicity receptor (NCR)

Indexed as

AsthmaHost-microbial interactionInnate lymphoid cellsMicrobiotaSputum

Identifiers

PMID34522438
PMCPMC8410993
OpenAlexW3183156272

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.