Evidence map›Paper›PMID 34522399›Full record

ReviewSultan Qaboos University medical journal2021

Management of Diabetes Insipidus following Surgery for Pituitary and Suprasellar Tumours.

Mussa H Almalki, Maswood M Ahmad, Imad Brema, Mohammed Almehthel, Khaled M AlDahmani, Moeber Mahzari, Salem A Beshyah

Open access · diamondAbstract readReview
In one paragraph

Review in Sultan Qaboos University medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
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  4. Letter to the Editor on the article, 'Journal of the ASEAN Federation of Endocrine Societies · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Integrating Polygenic Risk Scores (PRS) for Personalized Diabetes Care: Advancing Clinical Practice with Tailored Pharmacological Approaches.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025
    Review
  13. Article
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  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Mussa H AlmalkiObesity, Endocrine and Metabolism Centre, King Fahad Medical City, Riyadh, Saudi Arabia.
Maswood M AhmadObesity, Endocrine and Metabolism Centre, King Fahad Medical City, Riyadh, Saudi Arabia.
Imad BremaObesity, Endocrine and Metabolism Centre, King Fahad Medical City, Riyadh, Saudi Arabia.
Mohammed AlmehthelObesity, Endocrine and Metabolism Centre, King Fahad Medical City, Riyadh, Saudi Arabia.
Khaled M AlDahmaniDivision of Endocrinology, Tawam Hospital, Al Ain, United Arab Emirates.
Moeber MahzariFaculty of Medicine, King Saud Bin Abdul Aziz University of Health Sciences, Riyadh, Saudi Arabia.
Salem A BeshyahDepartment of Medicine, Dubai Medical College, Dubai, United Arab Emirates.
King Fahd Medical City · SAKing Saud bin Abdulaziz University for Health Sciences · SAMediclinic City Hospital · AEUnited Arab Emirates University · AEUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Central diabetes insipidus (CDI) is a common complication after pituitary surgery. However, it is most frequently transient. It is defined by the excretion of an abnormally large volume of dilute urine with increasing serum osmolality. The reported incidence of CDI after pituitary surgery ranges from 0-90%. Large tumour size, gross total resection and intraoperative cerebrospinal fluid leak usually pose an increased risk of CDI as observed with craniopharyngioma and Rathke's cleft cysts. CDI can be associated with high morbidity and mortality if not promptly recognised and treated on time. It is also essential to rule out other causes of postoperative polyuria to avoid unnecessary pharmacotherapy and iatrogenic hyponatremia. Once the diagnosis of CDI is established, close monitoring is required to evaluate the response to treatment and to determine whether the CDI is transient or permanent. This review outlines the evaluation and management of patients with CDI following pituitary and suprasellar tumour surgery to help recognise the diagnosis, consider the differential diagnosis, initiate therapeutic interventions and guide monitoring and long-term management.

Indexed as

Diabetes InsipidusDiabetes Insipidus, NeurogenicDiabetes MellitusNeoplasmsHumansArginine VasopressinCentral Diabetes InsipidusDesmopressinPituitary AdenomaPituitary SurgeryPolydipsiaPolyuriaPreoperative Risk FactorTreatment

Identifiers

PMID34522399
PMCPMC8407907
OpenAlexW3154557513

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.