Evidence map›Paper›PMID 34522389›Full record

ArticleVirus evolution2021

Comparative genomic analysis of genogroup 1 and genogroup 2 rotaviruses circulating in seven US cities, 2014-2016.

Mathew D Esona, Rashi Gautam, Eric Katz, Jose Jaime, M Leanne Ward, Mary E Wikswo, Naga S Betrapally, Slavica M Rustempasic, Rangaraj Selvarangan, Christopher J Harrison and 11 more

Open access · goldAbstract read
In one paragraph

Article in Virus evolution, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Genetic diversity of G9, G3, G8 and G1 rotavirus group A strains circulating among children with acute gastroenteritis in Vietnam from 2016 to 2021.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 7 institutions in 1 country.

Mathew D EsonaDivision of Viral Diseases, Centers for Disease Control and Prevention, Viral Gastroenteritis Branch, Atlanta, GA, USA.ORCID https://orcid.org/0000-0003-4069-947X
Rashi GautamDivision of Viral Diseases, Centers for Disease Control and Prevention, Viral Gastroenteritis Branch, Atlanta, GA, USA.
Eric KatzCherokee Nation Assurance, Contracting Agency to the Division of Viral Diseases, Centers for Disease Control and Prevention, Arlington, VA, USA.
Jose JaimeDivision of Viral Diseases, Centers for Disease Control and Prevention, Viral Gastroenteritis Branch, Atlanta, GA, USA.
M Leanne WardDivision of Viral Diseases, Centers for Disease Control and Prevention, Viral Gastroenteritis Branch, Atlanta, GA, USA.
Mary E WikswoDivision of Viral Diseases, Centers for Disease Control and Prevention, Viral Gastroenteritis Branch, Atlanta, GA, USA.
Naga S BetrapallyDivision of Viral Diseases, Centers for Disease Control and Prevention, Viral Gastroenteritis Branch, Atlanta, GA, USA.
Slavica M RustempasicDivision of Viral Diseases, Centers for Disease Control and Prevention, Viral Gastroenteritis Branch, Atlanta, GA, USA.
Rangaraj SelvaranganKansas City Children's Mercy Hospitals and Clinics, Kansas City, MO, USA.ORCID https://orcid.org/0000-0003-3275-6657
Christopher J HarrisonKansas City Children's Mercy Hospitals and Clinics, Kansas City, MO, USA.
Julie A BoomTexas Children's Hospital, Houston, TX, USA.
Jan EnglundSeattle Children's Hospital, Seattle, WA, USA.
Eileen J KleinSeattle Children's Hospital, Seattle, WA, USA.
Mary Allen StaatDivision of Infectious Diseases, Department of Pediatrics, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Monica M McNealDivision of Infectious Diseases, Department of Pediatrics, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Natasha HalasaVanderbilt University Medical Center, Nashville, TN, USA.
James ChappellVanderbilt University Medical Center, Nashville, TN, USA.
Geoffrey A WeinbergUniversity of Rochester School of Medicine and Dentistry, Rochester, NY, USA.
Daniel C PayneDivision of Viral Diseases, Centers for Disease Control and Prevention, Viral Gastroenteritis Branch, Atlanta, GA, USA.ORCID https://orcid.org/0000-0002-5871-911X
Umesh D ParasharDivision of Viral Diseases, Centers for Disease Control and Prevention, Viral Gastroenteritis Branch, Atlanta, GA, USA.
Michael D BowenDivision of Viral Diseases, Centers for Disease Control and Prevention, Viral Gastroenteritis Branch, Atlanta, GA, USA.
Centers for Disease Control and Prevention · USChildren's Mercy Hospital · USCincinnati Children's Hospital Medical Center · USSeattle Children's Hospital · USVanderbilt University Medical Center · USTexas Children's Hospital · USUniversity of Rochester · US

Funding

NCIRD CDC HHS U01 IP001049NCIRD CDC HHS U01 IP001158
6 · The paper itself

Abstract

For over a decade, the New Vaccine Surveillance Network (NVSN) has conducted active rotavirus (RVA) strain surveillance in the USA. The evolution of RVA in the post-vaccine introduction era and the possible effects of vaccine pressure on contemporary circulating strains in the USA are still under investigation. Here, we report the whole-gene characterization (eleven ORFs) for 157 RVA strains collected at seven NVSN sites during the 2014 through 2016 seasons. The sequenced strains included 52 G1P[8], 47 G12P[8], 18 G9P[8], 24 G2P[4], 5 G3P[6], as well as 7 vaccine strains, a single mixed strain (G9G12P[8]), and 3 less common strains. The majority of the single and mixed strains possessed a Wa-like backbone with consensus genotype constellation of G1/G3/G9/G12-P[8]-I1-R1-C1-M1-A1-N1-T1-E1-H1, while the G2P[4], G3P[6], and G2P[8] strains displayed a DS-1-like genetic backbone with consensus constellation of G2/G3-P[4]/P[6]/P[8]-I2-R2-C2-M2-A2-N2-T2-E2-H2. Two intergenogroup reassortant G1P[8] strains were detected that appear to be progenies of reassortment events between Wa-like G1P[8] and DS-1-like G2P[4] strains. Two Rotarix

Indexed as

allelesneutralization epitopesNVSNRVAUSAwhole-genome sequencing

Identifiers

PMID34522389
PMCPMC8432945
OpenAlexW3136317242

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.