Evidence map›Paper›PMID 34522101›Full record

ArticleTherapeutics and clinical risk management2021

Comparative Results Between "Epi-Off" Accelerated and "Epi-Off" Standard Corneal Collagen Crosslinking-UVA in Progressive Keratoconus - 7 Years of Follow-Up.

Cristina Ariadna Nicula, Anca Maria Rednik, Ariadna Patricia Nicula, Adriana Elena Bulboaca, Dorin Nicula, Karin Ursula Horvath

Open access · goldAbstract read
In one paragraph

Article in Therapeutics and clinical risk management, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Accelerated corneal cross-linking (18mW/cm2 for 5 min) with HPMC-riboflavin in progressive keratoconus - 5 years follow-up.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
  4. Corneal cross-linking in patients with keratoconus: up to 13 years of follow-up.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Cristina Ariadna NiculaDepartment of Ophthalmology, Medicine and Pharmacy University "Iuliu Hațieganu", Cluj-Napoca, Romania.ORCID 0000-0002-3222-6448
Anca Maria RednikEye County Hospital, Department of Ophthalmology, Cluj-Napoca, Romania.ORCID 0000-0002-3237-6200
Ariadna Patricia NiculaEye County Hospital, Department of Ophthalmology, Arad, Romania.
Adriana Elena BulboacaDepartment of Pathophysiology, Medicine and Pharmacy University "Iuliu Hațieganu", Cluj Napoca, Romania.ORCID 0000-0001-7748-382X
Dorin NiculaOculens Clinic, Cluj-Napoca, Romania.ORCID 0000-0002-4180-7949
Karin Ursula HorvathDepartment of Ophthalmology, Medicine and Pharmacy Science and Technology University "George Emil Palade", Târgu Mureș, Romania.ORCID 0000-0003-3166-2982
Iuliu Hațieganu University of Medicine and Pharmacy · ROArad County Clinical Hospital · ROUniversitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of the present study was to assess the long-term efficiency and safety of the "epi-off" accelerated CXL (9 mW/cm MATERIAL AND

methodA retrospective and comparative study was performed. A total of 183 eyes from 183 patients with documented progressive keratoconus were included in the study. The patients were divided in two groups: 93 eyes from 93 patients underwent "epi-off" standard cross-linking technique (3 mW/cm

resultsImprovements in uncorrected distance visual acuity (UDVA) were statistically significant compared to baseline values in both groups at each time-point visit (

conclusionThe long-term outcomes of "epi-off" accelerated corneal collagen crosslinking-UVA (9 mW/cm

Indexed as

accelerated cross-linkingkeratoconusprogressionstandard cross-linking

Identifiers

PMID34522101
PMCPMC8434931
OpenAlexW3198211446

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.