Evidence map›Paper›PMID 34522098›Full record

ArticleNeuropsychiatric disease and treatment2021

Relationship Between Mood Episode and Employment Status of Outpatients with Bipolar Disorder: Retrospective Cohort Study from the Multicenter Treatment Survey for Bipolar Disorder in Psychiatric Clinics (MUSUBI) Project.

Yusuke Konno, Yoshihisa Fujino, Atsuko Ikenouchi, Naoto Adachi, Yukihisa Kubota, Takaharu Azekawa, Hitoshi Ueda, Koji Edagawa, Eiichi Katsumoto, Eiichiro Goto and 8 more

Open access · goldAbstract read
In one paragraph

Article in Neuropsychiatric disease and treatment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Work impairment in bipolar disorder compared to the healthy population: a systematic review.Revista brasileira de medicina do trabalho : publicacao oficial da Associacao Nacional de Medicina do Trabalho-ANAMT
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 1 country.

Yusuke KonnoDepartment of Psychiatry, University of Occupational and Environmental Health, Kitakyushu, Japan.ORCID 0000-0001-7262-6916
Yoshihisa FujinoDepartment of Environmental Epidemiology, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Kitakyushu, Japan.
Atsuko IkenouchiDepartment of Psychiatry, University of Occupational and Environmental Health, Kitakyushu, Japan.ORCID 0000-0001-8328-4608
Naoto AdachiThe Japanese Association of Neuro-Psychiatric Clinics, Tokyo, Japan.ORCID 0000-0001-8376-4900
Yukihisa KubotaThe Japanese Association of Neuro-Psychiatric Clinics, Tokyo, Japan.ORCID 0000-0002-9837-6799
Takaharu AzekawaThe Japanese Association of Neuro-Psychiatric Clinics, Tokyo, Japan.ORCID 0000-0003-4294-4600
Hitoshi UedaThe Japanese Association of Neuro-Psychiatric Clinics, Tokyo, Japan.
Koji EdagawaThe Japanese Association of Neuro-Psychiatric Clinics, Tokyo, Japan.
Eiichi KatsumotoThe Japanese Association of Neuro-Psychiatric Clinics, Tokyo, Japan.
Eiichiro GotoThe Japanese Association of Neuro-Psychiatric Clinics, Tokyo, Japan.
Seiji HongoThe Japanese Association of Neuro-Psychiatric Clinics, Tokyo, Japan.
Masaki KatoThe Japanese Society of Clinical Neuropsychopharmacology, Tokyo, Japan.ORCID 0000-0001-6727-7272
Takashi TsuboiThe Japanese Society of Clinical Neuropsychopharmacology, Tokyo, Japan.ORCID 0000-0002-8253-8888
Norio Yasui-FurukoriThe Japanese Society of Clinical Neuropsychopharmacology, Tokyo, Japan.ORCID 0000-0002-4414-3770
Atsuo NakagawaThe Japanese Society of Clinical Neuropsychopharmacology, Tokyo, Japan.ORCID 0000-0002-2294-2571
Toshiaki KikuchiThe Japanese Society of Clinical Neuropsychopharmacology, Tokyo, Japan.
Koichiro WatanabeThe Japanese Society of Clinical Neuropsychopharmacology, Tokyo, Japan.ORCID 0000-0002-0736-7070
Reiji YoshimuraDepartment of Psychiatry, University of Occupational and Environmental Health, Kitakyushu, Japan.
University of Occupational and Environmental Health Japan · JPKeio University · JPKyorin University · JPJapanese Society of Clinical Neuropsychopharmacology · JPKansai Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe objective of this study was to clarify the relationship between mood episode and employment in patients with bipolar disorder to help improve their employment status.

methodsAll medical records of patients with bipolar disorder who visited 176 member clinics of the Japanese Association of Neuro-Psychiatric Clinics in September-October 2016 were investigated in September-October 2017. Details of the medical care received were investigated using a survey sheet, which included employment status. Odds ratios of mood episodes for employment status were analyzed using a logistic regression model.

resultsAmong patients aged 60 years or less, 2292 described their occupation. On univariate analysis, odds ratios were statistically significant for depressive episode (OR = 2.68 [1.50-4.78] p = 0.001) and manic episode (OR = 2.64 [1.07-6.47] p = 0.034), whereas no significant difference was noted for mixed episode (OR = 1.72 [0.69-4.33] p = 0.246). On multivariate analysis, odds ratios were statistically significant for depressive episode (OR = 2.16 [1.13-4.13], p = 0.020) and manic episode (OR = 3.55 [1.36-9.25], p = 0.010), whereas no significant difference was noted for mixed episode (OR = 1.83 [0.65-5.14] p = 0.254).

conclusionEmployment status among these patients with bipolar disorder receiving outpatient treatment was 43.5%. Compared to remission episodes, manic and depressive episodes were associated with a higher risk of unemployment.

Indexed as

continuous employmentJapanmood disorderoccupational health

Identifiers

PMID34522098
PMCPMC8434929
OpenAlexW3198002868

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.