ArticleCommunications biology2021
Evidence of shared and distinct functional and structural brain signatures in schizophrenia and autism spectrum disorder.
Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Convergent blood-brain barrier breakdown in schizophrenia and autism spectrum disorders: a systematic review of preclinical animal models.Fluids and barriers of the CNS · 2026Pooled it
- Uncovering convergence and divergence between autism and schizophrenia using genomic tools and patients' neurons.Molecular psychiatry · 2025Pooled it
- The Autism-Psychosis Continuum Conundrum: Exploring the Role of the Endocannabinoid System.International journal of environmental research and public health · 2022Pooled it
- Cerebellar Contributions to Cerebral Connectivity in Severe Mental Illness: A Developmental Cascade and Predictive-Modeling Framework with Autistic Disorder as the Focal Case.Brain sciences · 2026Review
- Evaluating the Prodromal Questionnaire-16 for Screening and Prediction of Psychosis in Autistic Adults: Cross-Sectional and Longitudinal Findings From a National Cohort.Schizophrenia bulletin · 2026Article
- The sixth sense of the brain: interoception in organoid study.Bone research · 2026Review
- An Orthogonal Semi-Nonnegative Matrix Factorization Method for Dynamic Functional Connectivity Analysis and Its Application to Schizophrenia.IEEE journal of biomedical and health informatics · 2026Article
- Robustness of NeuroMark-Derived Functional Networks to fMRI Spatial Normalization Across the Human Lifespan.bioRxiv : the preprint server for biology · 2026Article
- Brain functional network connectivity interpolation characterizes the neuropsychiatric continuum and heterogeneity.bioRxiv : the preprint server for biology · 2026Article
- BrainConnect: processing brain connectivity and spatial transcriptomics data for integrative analysis.Bioinformatics (Oxford, England) · 2026Article
- Differential connectivity between core hubs underlying demanding executive functions in schizophrenia compared to autism and control adults.Frontiers in psychiatry · 2026Article
- Multidimensional Comparisons Between Constrained ICA/IVA Algorithms for Multi-Subject fMRI Data Analysis.IEEE access : practical innovations, open solutions · 2026Article
- A graph transformer-based foundation model for brain functional connectivity network.Pattern recognition · 2026Article
- Cellular and molecular associations with intrinsic brain organization.Nature communications · 2025Article
- Cellular and molecular associations with intrinsic brain organization.bioRxiv : the preprint server for biology · 2025Article
- Neuroimage Analysis Methods and Artificial Intelligence Techniques for Reliable Biomarkers and Accurate Diagnosis of Schizophrenia: Achievements Made by Chinese Scholars Around the Past Decade.Schizophrenia bulletin · 2025Review
- Identifying overlapping and distinctive traits of autism and schizophrenia using machine learning classification.Cognitive neuropsychiatry · 2025Article
- Constrained Independent Vector Analysis With Reference for Multi-Subject fMRI Analysis.IEEE transactions on bio-medical engineering · 2024Article
- Shared Genetic Determinants of Schizophrenia and Autism Spectrum Disorder Implicate Opposite Risk Patterns: A Genome-Wide Analysis of Common Variants.Schizophrenia bulletin · 2024Article
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Corrections and comments
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Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
Abstract
Schizophrenia (SZ) and autism spectrum disorder (ASD) share considerable clinical features and intertwined historical roots. It is greatly needed to explore their similarities and differences in pathophysiologic mechanisms. We assembled a large sample size of neuroimaging data (about 600 SZ patients, 1000 ASD patients, and 1700 healthy controls) to study the shared and unique brain abnormality of the two illnesses. We analyzed multi-scale brain functional connectivity among functional networks and brain regions, intra-network connectivity, and cerebral gray matter density and volume. Both SZ and ASD showed lower functional integration within default mode and sensorimotor domains, but increased interaction between cognitive control and default mode domains. The shared abnormalties in intra-network connectivity involved default mode, sensorimotor, and cognitive control networks. Reduced gray matter volume and density in the occipital gyrus and cerebellum were observed in both illnesses. Interestingly, ASD had overall weaker changes than SZ in the shared abnormalities. Interaction between visual and cognitive regions showed disorder-unique deficits. In summary, we provide strong neuroimaging evidence of the convergent and divergent changes in SZ and ASD that correlated with clinical features.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.