Evidence map›Paper›PMID 34521963›Full record

Trial reportScientific reports2021

Clinical, functional and inflammatory evaluation in asthmatic patients after a simple short-term educational program: a randomized trial.

Soraia Nogueira Felix, Rosana Câmara Agondi, Marcelo Vivolo Aun, Clarice Rosa Olivo, Francine Maria de Almeida, Thais Santos Amorim, Julia Caroline Cezario, Pedro Giavina-Bianchi, Iolanda de Fátima Lopes Calvo Tiberio, Milton de Arruda de Martins and 1 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Soraia Nogueira FelixInstituto de Assistência Médica Ao Servidor Público Estadual (IAMSPE), Sao Paulo, SP, Brazil. soraia.ank@gmail.com.ORCID http://orcid.org/0000-0001-7353-5100
Rosana Câmara AgondiServiço de Imunologia Clínica e Alergia, HCFMUSP, Universidade de São Paulo, Sao Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-0503-5179
Marcelo Vivolo AunServiço de Imunologia Clínica e Alergia, HCFMUSP, Universidade de São Paulo, Sao Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-9882-5200
Clarice Rosa OlivoInstituto de Assistência Médica Ao Servidor Público Estadual (IAMSPE), Sao Paulo, SP, Brazil.
Francine Maria de AlmeidaLaboratório de Terapêutica Experimental (LIM-20), Faculdade de Medicina da USP (FMUSP), Universidade de Sao Paulo, Sao Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-9755-5034
Thais Santos AmorimUniversidade Cidade de Sao Paulo (UNICID), Sao Paulo, SP, Brazil.
Julia Caroline CezarioUniversidade Cidade de Sao Paulo (UNICID), Sao Paulo, SP, Brazil.
Pedro Giavina-BianchiServiço de Imunologia Clínica e Alergia, HCFMUSP, Universidade de São Paulo, Sao Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-1034-7580
Iolanda de Fátima Lopes Calvo TiberioLaboratório de Terapêutica Experimental (LIM-20), Faculdade de Medicina da USP (FMUSP), Universidade de Sao Paulo, Sao Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-5662-7895
Milton de Arruda de MartinsLaboratório de Terapêutica Experimental (LIM-20), Faculdade de Medicina da USP (FMUSP), Universidade de Sao Paulo, Sao Paulo, SP, Brazil.
Beatriz Mangueira Saraiva RomanholoInstituto de Assistência Médica Ao Servidor Público Estadual (IAMSPE), Sao Paulo, SP, Brazil. beatriz.msaraiva@fm.usp.br.ORCID http://orcid.org/0000-0003-0853-9708
Universidade Cidade de São Paulo · BRHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRUniversidade de São Paulo · BRHospital do Servidor Público Estadual · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the clinical evolution, functional parameters and inflammatory activity of asthma in patients who submitted to an educational intervention. 58 adult patients over 18 years of age with partly controlled and uncontrolled asthma were randomized into an intervention group (IG) (N = 32) and a control group (CG) (N = 26) and evaluated for 12 weeks. The Asthma Control Test (ACT), Asthma Control Questionnaire (ACQ), Asthma Quality Life Questionnaire (AQLQ) and Beck Depression Inventory (BDI) questionnaires were applied. Spirometry, exhaled nitric oxide (NO), exhaled breath condensate (EBC) and induced sputum (IS), measurement of the peak flow and symptoms were performed. The IG patients received an educational activity for 30 min applied by a nurse. Statistical analysis: analysis of variance with repeated intragroup measures. IG presented a decreased number of eosinophils in IS and IL-17A in EBC, an increase in the percentage of FEV

Indexed as

Patient Education as TopicAsthmaBreath TestsFemaleForced Expiratory VolumeHumansInflammationInterleukin-17Interleukin-4Interleukin-5MaleMiddle AgedNitric OxideQuality of LifeSpirometrySputumIL17A protein, humanIL4 protein, humanIL5 protein, humanInterleukin-17Interleukin-4Interleukin-5Nitric Oxide

Identifiers

PMID34521963
PMCPMC8440547
OpenAlexW3159694403

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.