ArticleScientific reports2021
Changes in muscle ultrasound for the diagnosis of intensive care unit acquired weakness in critically ill patients.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- A meta-analysis of the association between vasopressor use and intensive care unit-acquired weakness.Brain and behavior · 2024Pooled it
- Impact of Muscle Changes Assessed by Ultrasonography on Muscle Strength and Functioning after ICU Discharge: A Systematic Review with Meta-Analysis.International journal of environmental research and public health · 2024Pooled it
- The rate and assessment of muscle wasting during critical illness: a systematic review and meta-analysis.Critical care (London, England) · 2023Pooled it
- Clinical evaluation of AI-assisted muscle ultrasound for monitoring muscle wasting in ICU patients.Scientific reports · 2024Trial
- Methodological Approaches for Ultrasound Assessment of Peripheral and Abdominal Muscle Thickness in Intensive Care: A Scoping Review and Proposed Reporting Framework.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026Article
- Association between fluid balance, muscle strength, and muscle quality in critically ill patients: a retrospective observational study.Intensive care medicine experimental · 2026Article
- Muscle point-of-care ultrasound as a predictor of mortality in older adults with hip fracture.European geriatric medicine · 2026Observational
- Ultrasound assessment of muscle atrophy and its association with functional outcomes in critically ill patients: a systematic review and meta-analysis.Critical care (London, England) · 2026Review
- Assessment of muscle wasting in intensive care unit patients with and without COVID-19 using ultrasound imaging and bioimpedance analysis.BMC anesthesiology · 2026Article
- Changes in rectus femoris diameter: a cooperation-independent assessment method for ICU-acquired weakness.Frontiers in nutrition · 2026Article
- Reliability of Ultrasound Muscle Assessment in People With Critical Illness Performed by Occupational Therapy Students and Occupational Therapists.Occupational therapy international · 2026Article
- Dynamic changes in quadriceps and diaphragm thickness for early diagnosis of ICU-acquired weakness in elderly ICU patients: a prospective bedside ultrasound study.Frontiers in medicine · 2026Article
- Ultrasound monitoring of skeletal muscle wasting and relation to nutritional intervention in critically ill patients: MUScleNut study.Intensive care medicine experimental · 2025Article
- Prospective ultrasonographic evaluation of femoral and vastus intermedius muscles as predictors of ICU-acquired weakness in critically ill patients.Journal of ultrasound · 2025Article
- Differences in muscle atrophy between the lower limbs and the accessory respiratory muscles in critically ill patients.Journal of medical ultrasonics (2001) · 2025Article
- Development and validation of machine learning-based risk prediction models for ICU-acquired weakness: a prospective cohort study.European journal of medical research · 2025Article
- In vitro and in vivo muscle mass and strength during the first week of critical illness.Intensive care medicine experimental · 2025Article
- Potential diagnostic tools for intensive care unit acquired weakness: A systematic review.International journal of nursing studies advances · 2025Review
- Advancements in imaging techniques for monitoring the respiratory muscles.Critical care (London, England) · 2025Review
- The Utility of Muscle Ultrasound as a Predictor of Outcome in Guillain-Barré Syndrome Patients in the Intensive Care Unit: A Prospective Cohort Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To test diagnostic accuracy of changes in thickness (TH) and cross-sectional area (CSA) of muscle ultrasound for diagnosis of intensive care unit acquired weakness (ICU-AW). Fully conscious patients were subjected to muscle ultrasonography including measuring the changes in TH and CSA of biceps brachii (BB) muscle, vastus intermedius (VI) muscle, and rectus femoris (RF) muscles over time. 37 patients underwent muscle ultrasonography on admission day, day 4, day 7, and day 10 after ICU admission, Among them, 24 were found to have ICW-AW. Changes in muscle TH and CSA of RF muscle on the right side showed remarkably higher ROC-AUC and the range was from 0.734 to 0.888. Changes in the TH of VI muscle had fair ROC-AUC values which were 0.785 on the left side and 0.779 on the right side on the 10th day after ICU admission. Additionally, Sequential Organ Failure Assessment (SOFA), Acute Physiology, and Chronic Health Evaluation II (APACHE II) scores also showed good discriminative power on the day of admission (ROC-AUC 0.886 and 0.767, respectively). Ultrasonography of changes in muscles, especially in the TH of VI muscle on both sides and CSA of RF muscle on the right side, presented good diagnostic accuracy. However, SOFA and APACHE II scores are better options for early ICU-AW prediction due to their simplicity and time efficiency.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.