Evidence map›Paper›PMID 34521903›Full record

ArticleScientific reports2021

SARS-CoV-2 infection hospitalization, severity, criticality, and fatality rates in Qatar.

Shaheen Seedat, Hiam Chemaitelly, Houssein H Ayoub, Monia Makhoul, Ghina R Mumtaz, Zaina Al Kanaani, Abdullatif Al Khal, Einas Al Kuwari, Adeel A Butt, Peter Coyle and 10 more

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

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  16. Observational
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  18. Severity, Criticality, and Fatality of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Beta Variant.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Shaheen Seedat *Infectious Disease Epidemiology Group, Weill Cornell Medicine-Qatar, Cornell University, Doha, Qatar.
Hiam Chemaitelly *Infectious Disease Epidemiology Group, Weill Cornell Medicine-Qatar, Cornell University, Doha, Qatar.
Houssein H Ayoub *Department of Mathematics, Statistics, and Physics, Qatar University, Doha, Qatar.
Monia MakhoulInfectious Disease Epidemiology Group, Weill Cornell Medicine-Qatar, Cornell University, Doha, Qatar.
Ghina R MumtazDepartment of Epidemiology and Population Health, American University of Beirut, Beirut, Lebanon.
Zaina Al KanaaniHamad Medical Corporation, Doha, Qatar.
Abdullatif Al KhalHamad Medical Corporation, Doha, Qatar.
Einas Al KuwariHamad Medical Corporation, Doha, Qatar.
Adeel A ButtDepartment of Population Health Sciences, Weill Cornell Medicine, Cornell University, New York, NY, USA.
Peter CoyleHamad Medical Corporation, Doha, Qatar.
Andrew JeremijenkoHamad Medical Corporation, Doha, Qatar.
Anvar Hassan KaleeckalHamad Medical Corporation, Doha, Qatar.
Ali Nizar LatifHamad Medical Corporation, Doha, Qatar.
Riyazuddin Mohammad ShaikHamad Medical Corporation, Doha, Qatar.
Hadi M YassineBiomedical Research Center, Qatar University, Doha, Qatar.
Mohamed G Al KuwariPrimary Health Care Corporation, Doha, Qatar.
Hamad Eid Al RomaihiMinistry of Public Health, Doha, Qatar.
Mohamed H Al-ThaniMinistry of Public Health, Doha, Qatar.
Roberto BertolliniMinistry of Public Health, Doha, Qatar.
Laith J Abu-RaddadInfectious Disease Epidemiology Group, Weill Cornell Medicine-Qatar, Cornell University, Doha, Qatar. lja2002@qatar-med.cornell.edu.

Funding

Qatar National Research Fund NPRP grant number 9-040-3-008UK Research and Innovation as part of the Global Challenges Research Fund Grant number ES/P010873/1
6 · The paper itself

Abstract

The SARS-CoV-2 pandemic resulted in considerable morbidity and mortality as well as severe economic and societal disruptions. Despite scientific progress, true infection severity, factoring both diagnosed and undiagnosed infections, remains poorly understood. This study aimed to estimate SARS-CoV-2 age-stratified and overall morbidity and mortality rates based on analysis of extensive epidemiological data for the pervasive epidemic in Qatar, a country where < 9% of the population are ≥ 50 years. We show that SARS-CoV-2 severity and fatality demonstrate a striking age dependence with low values for those aged < 50 years, but rapidly growing rates for those ≥ 50 years. Age dependence was particularly pronounced for infection criticality rate and infection fatality rate. With Qatar's young population, overall SARS-CoV-2 severity and fatality were not high with < 4 infections in every 1000 being severe or critical and < 2 in every 10,000 being fatal. Only 13 infections in every 1000 received any hospitalization in acute-care-unit beds and < 2 in every 1000 were hospitalized in intensive-care-unit beds. However, we show that these rates would have been much higher if Qatar's population had the demographic structure of Europe or the United States. Epidemic expansion in nations with young populations may lead to considerably lower disease burden than currently believed.

Indexed as

AdolescentAdultAgedAged, 80 and overChildChild, PreschoolCOVID-19FemaleHospitalizationHumansInfantInfant, NewbornIntensive Care UnitsMaleMiddle AgedQatar

Identifiers

PMID34521903
PMCPMC8440606

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.