ArticleNature communications2021
Parental relatedness through time revealed by runs of homozygosity in ancient DNA.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 161 papers, 1 of them a synthesis that pooled it.
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Who cites it
161 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Declining autozygosity over time: An exploration in over 1 million individuals from three diverse cohorts.American journal of human genetics · 2023Pooled it
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- Ancient DNA Reveals Limited Hunter-Gatherer Ancestry in the Cerny Culture (Middle Neolithic, France) Despite Hunting-Associated Practices.American journal of biological anthropology · 2026Article
- Genomic characterization of historical Jinlingnan individuals: insights into genetic continuity and trans-Eurasian signals in eastern China.Human genetics · 2026Article
- Ancient genomics study reveals low HLA diversity in eastern hunter-gatherers.Genome biology · 2026Article
- High-coverage ancient genomes reveal divergent population histories and prehistoric starch-related genetic variation in Japan.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Genetic identification of Árpád Dynasty members from the ossuary of the Royal Basilica at Székesfehérvár.iScience · 2026Article
- Ancestry, admixture, and pathogens in contemporaneous Neolithic farmers and foragers on the Island of Gotland.Communications biology · 2026Article
- Equal in death: Ancient genomic analysis of children's early Christian burials.Science advances · 2026Article
- Ancient DNA reveals elite dynastic rule among Iron Age Eurasian Steppe nomads.Science advances · 2026Article
- Ancient DNA evidence for the history of the Albanians.Nature human behaviour · 2026Article
- Comparing the genomic inbreeding of an isolated rhesus macaque study population to wild populations.bioRxiv : the preprint server for biology · 2026Article
- Mesopotamian ancient DNA reveals Iron Age integration of heterogeneous Bronze Age genetic ancestries following resettlement.Genome biology · 2026Article
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- Bioarchaeological analysis illustrates the life of a 16th-century Sámi individual from Kitka, Kuusamo, northern Finland.BMC genomics · 2026Article
- Ancient DNA reveals a family ossuary and long-distance migration on the Pacific coast before the Inca Empire.Nature communications · 2026Article
- First Lithic Age Caribbean genomes document pre-Ceramic genetic continuity and affinities to Central America and northern South America.bioRxiv : the preprint server for biology · 2026Article
- Kinship Trouble: What, When, Where, Why, and How-and So What?Cambridge archaeological journal · 2026Article
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101 more citing papers are in PubMed but not listed here.
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Abstract
Parental relatedness of present-day humans varies substantially across the globe, but little is known about the past. Here we analyze ancient DNA, leveraging that parental relatedness leaves genomic traces in the form of runs of homozygosity. We present an approach to identify such runs in low-coverage ancient DNA data aided by haplotype information from a modern phased reference panel. Simulation and experiments show that this method robustly detects runs of homozygosity longer than 4 centimorgan for ancient individuals with at least 0.3 × coverage. Analyzing genomic data from 1,785 ancient humans who lived in the last 45,000 years, we detect low rates of first cousin or closer unions across most ancient populations. Moreover, we find a marked decay in background parental relatedness co-occurring with or shortly after the advent of sedentary agriculture. We observe this signal, likely linked to increasing local population sizes, across several geographic transects worldwide.
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