Evidence map›Paper›PMID 34521806›Full record

ArticleSignal transduction and targeted therapy2021

Targeting chaperon protein HSP70 as a novel therapeutic strategy for FLT3-ITD-positive acute myeloid leukemia.

Chen Hu, Fengming Zou, Aoli Wang, Weili Miao, Qianmao Liang, Ellen L Weisberg, Yinsheng Wang, Jing Liu, Wenchao Wang, Qingsong Liu

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Signal transduction and targeted therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
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  3. Article
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  5. Exploring the Anticancer Potential ofPlants (Basel, Switzerland) · 2023
    Article
  6. Review
  7. Review
  8. Review
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  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chen Hu *Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, People's Republic of China.
Fengming Zou *Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, People's Republic of China.
Aoli Wang *Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, People's Republic of China.
Weili MiaoDepartment of Chemistry, University of California-Riverside, Riverside, CA, USA.
Qianmao LiangAnhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, People's Republic of China.
Ellen L WeisbergDepartment of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
Yinsheng WangDepartment of Chemistry, University of California-Riverside, Riverside, CA, USA.
Jing LiuAnhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, People's Republic of China. jingliu@hmfl.ac.cn.
Wenchao WangAnhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, People's Republic of China. wwcbox@hmfl.ac.cn.
Qingsong LiuAnhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, People's Republic of China. qsliu97@hmfl.ac.cn.ORCID 0000-0002-7829-2547

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug TaperingAntineoplastic Agentsfms-Like Tyrosine Kinase 3HEK293 CellsHSP70 Heat-Shock ProteinsHumansLeukemia, Myeloid, AcuteAntineoplastic AgentsFLT3 protein, humanfms-Like Tyrosine Kinase 3HSP70 Heat-Shock Proteins

Identifiers

PMID34521806
PMCPMC8440619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.