Evidence map›Paper›PMID 34521731›Full record

ArticleRNA (New York, N.Y.)2021

Shortening of 3' UTRs in most cell types composing tumor tissues implicates alternative polyadenylation in protein metabolism.

Dominik Burri, Mihaela Zavolan

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Dominik BurriComputational and Systems Biology, Biozentrum, University of Basel, Basel, CH-4056, Switzerland SIB Swiss Institute of Bioinformatics, Basel, CH-4056, Switzerland.ORCID 0000-0002-8131-9309
Mihaela ZavolanComputational and Systems Biology, Biozentrum, University of Basel, Basel, CH-4056, Switzerland SIB Swiss Institute of Bioinformatics, Basel, CH-4056, Switzerland.ORCID 0000-0002-8832-2041
SIB Swiss Institute of Bioinformatics · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During pre-mRNA maturation 3' end processing can occur at different polyadenylation sites in the 3' untranslated region (3' UTR) to give rise to transcript isoforms that differ in the length of their 3' UTRs. Longer 3' UTRs contain additional

Indexed as

Gene Expression Regulation, NeoplasticPolyadenylation3' Untranslated RegionsAdenocarcinoma of LungCase-Control StudiesHumansLung NeoplasmsProtein IsoformsRNA, Messenger3' Untranslated RegionsProtein IsoformsRNA, Messengeralternative polyadenylationbioinformaticscomputational methodlung cancersingle cell transcriptomics

Identifiers

PMID34521731
PMCPMC8594477
OpenAlexW3200242554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.