Evidence map›Paper›PMID 34521667›Full record

ArticleBMJ open2021

COVID-19 in Pregnancy and Early Childhood (COPE): study protocol for a prospective, multicentre biobank, survey and database cohort study.

Ylva Carlsson, Lina Bergman, Mehreen Zaigham, Karolina Linden, Ola Andersson, Malin Veje, Anna Sandström, Anna-Karin Wikström, Hanna Östling, Helena Fadl and 6 more

Registry-linked trialOpen access · goldAbstract readMulticenter Study
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04433364 (COPE - COVID-19 in Pregnancy and Early Childhood - a Study Protocol for a Prospective Multicentre Cohort Study), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04433364 active not recruitingnot on this map

COPE - COVID-19 in Pregnancy and Early Childhood - a Study Protocol for a Prospective Multicentre Cohort Study

Typeobservational_patient_registrySponsorSahlgrenska University HospitalRan2020 to 2040Enrolled3,834ConditionsSars-CoV2, Covid-19, Pregnancy Complications, Pregnancy PretermArmsbiological samples, questionnaires and interviews
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 10 institutions in 1 country.

Ylva CarlssonDepartment of Obstetrics and Gynaecologyhe, Institute of Clinical Science, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0002-1414-7279
Lina BergmanDepartment of Obstetrics and Gynaecologyhe, Institute of Clinical Science, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0001-5202-9428
Mehreen ZaighamDepartment of Clinical Sciences Lund, Lund University, Lund, Sweden.ORCID 0000-0003-0129-1578
Karolina LindenInstitute of Health and Care Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0002-2792-3142
Ola AnderssonDepartment of Clinical Sciences Lund, Pediatrics, Lund University and Skåne University Hospital, Malmö, Sweden.ORCID 0000-0002-3972-0457
Malin VejeDepartment of Infectious Diseases, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0001-5487-0616
Anna SandströmDepartment of Medicine, Solna, Clinical Epidemiology Division, Karolinska Institutet, Stockholm, Sweden.
Anna-Karin WikströmDepartment of Women's and Childen's Health, Uppsala University, Uppsala, Sweden.
Hanna ÖstlingDepartment of Obstetrics and Gynaecology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Helena FadlDepartment of Obstetrics and Gynaecology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.ORCID 0000-0002-2691-7525
Magnus DomellöfDepartment of Clinical Sciences, Pediatrics, Umeå University, Umeå, Sweden.ORCID 0000-0002-0726-7029
Marie BlombergDepartment of Obstetrics and Gynecology and Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.ORCID 0000-0003-4679-550X
Sophia Brismar WendelDepartment of Clinical Sciences, Karolinska Institutet Danderyd Hospital, Stockholm, Sweden.ORCID 0000-0002-9401-8062
Ulrika ÅdenDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Verena SengpielDepartment of Obstetrics and Gynaecologyhe, Institute of Clinical Science, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden verena.sengpiel@obgyn.gu.se.ORCID 0000-0002-3608-7430
COPE study group
Sahlgrenska University Hospital · SELund University · SEÖrebro University · SEDanderyds sjukhus · SEKarolinska Institutet · SEKarolinska University Hospital · SELinköping University · SEUmeå University · SEUniversity of Gothenburg · SEUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThere is limited knowledge on how the SARS-CoV-2 affects pregnancy outcomes. Studies investigating the impact of COVID-19 in early pregnancy are scarce and information on long-term follow-up is lacking.The purpose of this project is to study the impact of COVID-19 on pregnancy outcomes and long-term maternal and child health by: (1) establishing a database and biobank from pregnant women with COVID-19 and presumably non-infected women and their infants and (2) examining how women and their partners experience pregnancy, childbirth and early parenthood in the COVID-19 pandemic. METHODS AND ANALYSIS: This is a national, multicentre, prospective cohort study involving 27 Swedish maternity units accounting for over 86 000 deliveries/year. Pregnant women are included when they: (1) test positive for SARS-CoV-2 (COVID-19 group) or (2) are non-infected and seek healthcare at one of their routine antenatal visits (screening group). Blood, as well as other biological samples, are collected at different time points during and after pregnancy. Child health up to 4 years of age and parent experience of pregnancy, delivery, early parenthood, healthcare and society in general will be examined using web-based questionnaires based on validated instruments. Short- and long-term health outcomes will be collected from Swedish health registers and the parents' experiences will be studied by performing qualitative interviews. ETHICS AND DISSEMINATION: Confidentiality aspects such as data encryption and storage comply with the General Data Protection Regulation and with ethical committee requirements. This study has been granted national ethical approval by the Swedish Ethical Review Authority (dnr 2020-02189 and amendments 2020-02848, 2020-05016, 2020-06696 and 2021-00870) and national biobank approval by the Biobank Väst (dnr B2000526:970). Results from the project will be published in peer-reviewed journals. TRIAL REGISTRATION NUMBER: NCT04433364.

Indexed as

COVID-19Biological Specimen BanksChild, PreschoolCohort StudiesFemaleHumansMulticenter Studies as TopicPandemicsPregnancyPregnancy OutcomeProspective StudiesSARS-CoV-2Surveys and QuestionnairesCOVID-19epidemiologyneonatologyobstetrics

Identifiers

PMID34521667
PMCPMC8441224
OpenAlexW3200123201

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.