Evidence map›Paper›PMID 34521666›Full record

Observational studyBMJ open2021

Assessing the safety of home oximetry for COVID-19: a multisite retrospective observational study.

Jonathan Clarke, Kelsey Flott, Roberto Fernandez Crespo, Hutan Ashrafian, Gianluca Fontana, Jonathan Benger, Ara Darzi, Sarah Elkin

Abstract readObservational Study
In one paragraph

Observational study in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jonathan ClarkeCentre for Mathematics of Precision Healthcare, Imperial College London, London, UK j.clarke@imperial.ac.uk.ORCID 0000-0003-1495-7746
Kelsey FlottInstitute of Global Health Innovation, Imperial College London, London, UK.
Roberto Fernandez CrespoInstitute of Global Health Innovation, Imperial College London, London, UK.
Hutan AshrafianInstitute of Global Health Innovation, Imperial College London, London, UK.ORCID 0000-0003-1668-0672
Gianluca FontanaInstitute of Global Health Innovation, Imperial College London, London, UK.
Jonathan BengerNHS Digital, Leeds, UK.ORCID 0000-0001-6131-0916
Ara DarziInstitute of Global Health Innovation, Imperial College London, London, UK.
Sarah ElkinNational Heart and Lung Institute, Imperial College London, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo determine the safety and effectiveness of home oximetry monitoring pathways for patients with COVID-19 in the English National Health Service.

designRetrospective, multisite, observational study of home oximetry monitoring for patients with suspected or proven COVID-19.

settingThis study analysed patient data from four COVID-19 home oximetry pilot sites in England across primary and secondary care settings.

participantsA total of 1338 participants were enrolled in a home oximetry programme across four pilot sites. Participants were excluded if primary care data and oxygen saturations at rest at enrolment were not available. Data from 908 participants were included in the analysis.

interventionsHome oximetry monitoring was provided to participants with a known or suspected diagnosis of COVID-19. Participants were enrolled following attendance to emergency departments, hospital admission or referral through primary care services.

resultsOf 908 patients enrolled into four different COVID-19 home oximetry programmes in England, 771 (84.9%) had oxygen saturations at rest of 95% or more, and 320 (35.2%) were under 65 years of age and without comorbidities. 52 (5.7%) presented to hospital and 28 (3.1%) died following enrolment, of which 14 (50%) had COVID-19 as a named cause of death. All-cause mortality was significantly higher in patients enrolled after admission to hospital (OR 8.70 (2.53-29.89)), compared with those enrolled in primary care. Patients enrolled after hospital discharge (OR 0.31 (0.15-0.68)) or emergency department presentation (OR 0.42 (0.20-0.89)) were significantly less likely to present to hospital than those enrolled in primary care.

conclusionsThis study finds that home oximetry monitoring can be a safe pathway for patients with COVID-19; and indicates increases in risk to vulnerable groups and patients with oxygen saturations <95% at enrolment, and in those enrolled on discharge from hospital. Findings from this evaluation have contributed to the national implementation of home oximetry across England.

Indexed as

COVID-19HumansOximetryRetrospective StudiesSARS-CoV-2State MedicineCOVID-19primary carepublic healthrespiratory medicine (see thoracic medicine)telemedicine

Identifiers

PMID34521666
PMCPMC8441226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.