ArticleParasites & vectors2021
Phylogeography and population differentiation in Hepatozoon canis (Apicomplexa: Hepatozoidae) reveal expansion and gene flow in world populations.
Article in Parasites & vectors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 22 citations in OpenAlex.
- Hepatozoon martis in Italy: first evidence based on histopathological characterization and molecular confirmation in Martes foina.Parasites & vectors · 2026Article
- Mass spectrometry-based serum peptidomic profiling reveals potential biomarker for canine hepatozoonosis.Scientific reports · 2025Article
- Hepatozoon infections in domestic and wild Carnivora: etiology, prevalence, clinical disease, diagnosis and treatment, and redescription of Hepatozoon silvestris, H. martis, and H. ursi.Parasites & vectors · 2025Review
- Fatal babesiosis in a free-ranging iberian wolf co-infected withInternational journal for parasitology. Parasites and wildlife · 2025Article
- Genetic structure and evolutionary dynamics of Babesia gibsoni populations: a cytochrome oxidase subunit I (COXI) gene-based study.BMC veterinary research · 2025Article
- Host switching is the main driver of coevolution between Hepatozoon parasites and their vertebrate hosts.Parasites & vectors · 2025Article
- Integrative taxonomy in helminth analysis: protocols and limitations in the twenty-first century.Parasites & vectors · 2025Review
- Molecular characterization ofOpen veterinary journal · 2025Article
- Geographical isolation and hyperendemicity ofCurrent research in parasitology & vector-borne diseases · 2024Article
- Genetic Diversity and Population Dynamics ofVeterinary medicine international · 2024Article
- New records, and molecular detection of vector-borne pathogens in Felicola subrostratus from eastern Mexico.Veterinary research communications · 2023Article
- Hepatozoon spp. infection in wild canids in the eastern United States.Parasites & vectors · 2023Article
- Molecular Survey and Genetic Characteristics of Vector-Borne Pathogens in Domestic Dogs from Four Regions of China.Animals : an open access journal from MDPI · 2023Article
- ElucidatingFrontiers in parasitology · 2023Article
- Analysis of genetic diversity and population structure ofFrontiers in veterinary science · 2023Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHepatozoon canis is a protozoan transmitted to dogs and other wild carnivores by the ingestion of ticks containing mature oocysts and is considered the principal cause of canine hepatozoonosis in the world. Here, we examined ribosomal RNA 18S gene sequence variation to determine the genetic differences and phylogeographic diversity of H. canis from various geographical areas around the world.
methodsWe used 550 publicly available sequences of H. canis from 46 countries to assess haplotype relationships, geographical structure, genetic diversity indices, and relationships among populations. We performed neutrality tests and pairwise comparisons of fixation index (F
resultsThe dataset of H. canis yielded 76 haplotypes. Differentiation among populations indicated that there is no phylogeographical structure (G
conclusionsThe current molecular data confirmed that H. canis does not show phylogeographic or population structure. The haplotypes exhibit low genetic differentiation, suggesting a recent expansion due to gene flow among populations. These results provide pivotal information required for future detailed population genetic analysis or to establish control strategies of this parasite.
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