Evidence map›Paper›PMID 34521377›Full record

ArticleBMC pregnancy and childbirth2021

Methods of induction of labor and women's experience: a population-based cohort study with mediation analyses.

Pauline Blanc-Petitjean, Corinne Dupont, Bruno Carbonne, Marina Salomé, François Goffinet, Camille Le Ray, MEDIP study group

Open access · goldAbstract readComparative Study
In one paragraph

Article in BMC pregnancy and childbirth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Prevalence and risk factors of maternal dissatisfaction after vaginal delivery: A multicenter prospective study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Pauline Blanc-PetitjeanUniversité de Paris, CRESS, INSERM, INRA, F-75004, Paris, France. pauline.blanc-petitjean@inserm.fr.
Corinne DupontRéseau périnatal Aurore - Hôpital de la Croix Rousse, Université Lyon 1, HESPER EA 7425 Health Services and Performance Research, F-69008, Lyon, France.
Bruno CarbonneDepartment of Obstetrics and Gynecology, Princess Grace Hospital, Monaco, France.
Marina SaloméAP-HP, URC-CIC Paris Descartes Necker/Cochin, F-75014, Paris, France.
François GoffinetUniversité de Paris, CRESS, INSERM, INRA, F-75004, Paris, France.
Camille Le RayUniversité de Paris, CRESS, INSERM, INRA, F-75004, Paris, France.
MEDIP study group
Inserm · FRPrincess Grace Hospital Centre · MCUniversité Claude Bernard Lyon 1 · FRUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNegative childbirth experience may affect mother wellbeing and health. However, it is rarely evaluated in studies comparing methods of induction of labor (IoL).

aimTo compare women's experience of IoL according to the method, considering the mediating role of interventions and complications of delivery.

methodsWe used data from the MEDIP prospective population-based cohort, including all women with IoL during one month in seven French perinatal networks. The experience of IoL, assessed at 2 months postpartum, was first compared between cervical ripening and oxytocin, and secondarily between different cervical ripening methods. Mediation analyses were used to measure the direct and indirect effects of cervical ripening on maternal experience, through delivery with interventions or complications.

findingsThe response rate was 47.8% (n = 1453/3042). Compared with oxytocin (n = 541), cervical ripening (n = 910) was associated less often with feelings that labor went 'as expected' (adjusted risk ratio for the direct effect 0.78, 95%CI [0.70-0.88]), length of labor was 'acceptable' (0.76[0.71-0.82]), 'vaginal discomfort' was absent (0.77[0.69-0.85]) and with lower global satisfaction (0.90[0.84-0.96]). Interventions and complications mediated between 6 and 35% of the total effect of cervical ripening on maternal experience. Compared to the dinoprostone insert, maternal experience was not significantly different with the other prostaglandins. The balloon catheter was associated with less pain. DISCUSSION: Cervical ripening was associated with a less positive experience of childbirth, whatever the method, only partly explained by interventions and complications of delivery.

conclusionCounselling and support of women requiring cervical ripening might be enhanced to improve the experience of IoL.

Indexed as

Patient SatisfactionAdultCervical RipeningCohort StudiesFemaleFranceHumansLabor, InducedMediation AnalysisOxytocicsOxytocinPregnancyProspective StudiesYoung AdultOxytocicsOxytocinCervical ripeningInduction of laborMaternal experience, midwifery research, causal mediation analysis

Identifiers

PMID34521377
PMCPMC8442398
OpenAlexW3200485291

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.