ArticleBMC infectious diseases2021
Clinical characteristics and risk factors of fatal patients with COVID-19: a retrospective cohort study in Wuhan, China.
Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Effects of the pre-existing coronary heart disease on the prognosis of COVID-19 patients: A systematic review and meta-analysis.PloS one · 2023Pooled it
- [Experiences from SARS-CoV-2 pandemic at UKSH Lübeck].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2026Article
- Article
- The V-shaped association between the ratio of neutrophil counts to prognostic nutritional index and 30-, 60-, and 90-day mortality in elderly critically ill patients aged 65 and older with sepsis: a retrospective study based on the MIMIC database.Frontiers in nutrition · 2025Article
- Development and validation of a scoring system to predict the mortality of hospitalized patients with SARS-CoV-2 Omicron: a nationwide, multicentre study.BMC pulmonary medicine · 2024Article
- Decoding acute myocarditis in patients with COVID-19: Early detection through machine learning and hematological indices.iScience · 2024Article
- Case-control study on risk factors for in-hospital mortality in patients with severe COVID-19.Frontiers in public health · 2024Observational
- Creating a provincial post COVID-19 interdisciplinary clinical care network as a learning health system during the pandemic: Integrating clinical care and research.Learning health systems · 2023Article
- Red blood cell distribution width at admission predicts outcome in critically ill patients with kidney failure: a retrospective cohort study based on the MIMIC-IV database.Renal failure · 2022Article
- Ivermectin: A Controversial Focal Point during the COVID-19 Pandemic.Life (Basel, Switzerland) · 2022Review
- Rare case of pneumoperitoneum in nonintubated COVID-19 patient.Clinical case reports · 2022Article
- Article
- Predicting progression to severe COVID-19 using the PAINT score.BMC infectious diseases · 2022Article
- SARS-CoV-2 triggered oxidative stress and abnormal energy metabolism in gut microbiota.MedComm · 2022Article
- Analysis of Deaths and Favorable Developments of Patients with SARS-CoV-2 Hospitalized in the Largest Hospital for Infectious Diseases and Pneumo-Phthisiology in the West of the Country.International journal of general medicine · 2022Article
- Article
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Authors and funding
31 authors at 7 institutions in 1 country.
Funding
Abstract
backgroundThe coronavirus disease 2019 (COVID-19) has caused a global pandemic, resulting in considerable mortality. The risk factors, clinical treatments, especially comprehensive risk models for COVID-19 death are urgently warranted.
methodsIn this retrospective study, 281 non-survivors and 712 survivors with propensity score matching by age, sex, and comorbidities were enrolled from January 13, 2020 to March 31, 2020.
resultsHigher SOFA, qSOFA, APACHE II and SIRS scores, hypoxia, elevated inflammatory cytokines, multi-organ dysfunction, decreased immune cell subsets, and complications were significantly associated with the higher COVID-19 death risk. In addition to traditional predictors for death risk, including APACHE II (AUC = 0.83), SIRS (AUC = 0.75), SOFA (AUC = 0.70) and qSOFA scores (AUC = 0.61), another four prediction models that included immune cells subsets (AUC = 0.90), multiple organ damage biomarkers (AUC = 0.89), complications (AUC = 0.88) and inflammatory-related indexes (AUC = 0.75) were established. Additionally, the predictive accuracy of combining these risk factors (AUC = 0.950) was also significantly higher than that of each risk group alone, which was significant for early clinical management for COVID-19.
conclusionsThe potential risk factors could help to predict the clinical prognosis of COVID-19 patients at an early stage. The combined model might be more suitable for the death risk evaluation of COVID-19.
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